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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDUFA2 All Species: 54.24
Human Site: S59 Identified Species: 85.24
UniProt: O43678 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43678 NP_002479.1 99 10922 S59 P I L I R E C S D V Q P K L W
Chimpanzee Pan troglodytes XP_517976 99 10975 S59 P I L I R E C S D V Q P K L W
Rhesus Macaque Macaca mulatta XP_001087963 99 10944 S59 P I L I R E C S D V Q P K L W
Dog Lupus familis XP_535211 99 10857 S59 P I L I R E C S D V Q P K L W
Cat Felis silvestris
Mouse Mus musculus Q9CQ75 99 10897 S59 P I L I R E C S E V Q P K L W
Rat Rattus norvegicus NP_001099623 97 10826 S57 P I L I R E C S E V Q P K L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512375 99 10865 S58 P V L I R E C S A V Q P K L W
Chicken Gallus gallus XP_001232016 100 11052 S60 P I L I R E C S G V Q P R L W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019591 101 11057 S61 P I L I R E C S G V Q P V L W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122762 128 15098 S87 P I L I R E C S L I E P I L Y
Nematode Worm Caenorhab. elegans NP_493465 92 10186 S53 P I L I R E A S G I V P R V F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002299367 98 10986 N54 P I L I R E C N G I E P Q L W
Maize Zea mays NP_001150163 99 11083 S54 P F L V R E C S G V Q P Q L W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199600 97 10832 S54 P I L I R E C S G V Q P Q M W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q07842 94 10512 S54 P I L I R D A S G T L P K V Y
Conservation
Percent
Protein Identity: 100 95.9 97.9 85.8 N.A. 85.8 83.8 N.A. 70.7 65 N.A. 65.3 N.A. N.A. 39.8 44.4 N.A.
Protein Similarity: 100 98.9 98.9 91.9 N.A. 93.9 90.9 N.A. 79.8 80 N.A. 76.2 N.A. N.A. 53.9 58.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 86.6 N.A. 86.6 N.A. N.A. 66.6 53.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 86.6 N.A. N.A. 86.6 80 N.A.
Percent
Protein Identity: 50.5 43.4 N.A. 52.5 N.A. 33.3
Protein Similarity: 64.6 60.6 N.A. 66.6 N.A. 51.5
P-Site Identity: 66.6 73.3 N.A. 80 N.A. 53.3
P-Site Similarity: 93.3 86.6 N.A. 93.3 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 14 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 87 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 27 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 94 0 0 14 0 14 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 87 0 94 0 0 0 0 0 20 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 54 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 7 0 7 0 0 80 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 100 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 74 0 20 0 0 % Q
% Arg: 0 0 0 0 100 0 0 0 0 0 0 0 14 0 0 % R
% Ser: 0 0 0 0 0 0 0 94 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 0 7 0 7 0 0 0 0 0 74 7 0 7 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _