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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BUB1
All Species:
4.55
Human Site:
S436
Identified Species:
25
UniProt:
O43683
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43683
NP_004327.1
1085
122375
S436
T
H
K
V
A
N
T
S
S
F
H
T
T
P
N
Chimpanzee
Pan troglodytes
XP_001142040
1085
122293
S436
T
H
K
V
A
N
T
S
S
F
H
T
T
P
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O08901
1058
119544
N424
T
N
K
V
A
S
I
N
D
F
H
T
T
P
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782910
1533
171372
A700
T
P
S
S
A
S
F
A
S
L
S
R
S
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P41695
1021
117850
H410
N
P
S
Q
S
T
H
H
K
N
T
Q
V
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
N.A.
N.A.
N.A.
72
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.3
N.A.
N.A.
N.A.
82.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
42.3
P-Site Identity:
100
100
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
80
0
0
20
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
20
0
0
60
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
40
0
0
0
0
20
20
0
0
60
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
60
0
0
0
0
0
20
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
20
0
0
0
40
0
20
0
20
0
0
0
0
80
% N
% Pro:
0
40
0
0
0
0
0
0
0
0
0
0
0
60
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
0
20
0
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
20
0
20
0
% R
% Ser:
0
0
40
20
20
40
0
40
60
0
20
0
20
0
0
% S
% Thr:
80
0
0
0
0
20
40
0
0
0
20
60
60
0
0
% T
% Val:
0
0
0
60
0
0
0
0
0
0
0
0
20
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _