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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BUB3 All Species: 50.91
Human Site: S176 Identified Species: 70
UniProt: O43684 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43684 NP_001007794.1 328 37155 S176 Y V Q Q R R E S S L K Y Q T R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105368 335 37958 S176 Y V Q Q R R E S S L K Y Q T R
Dog Lupus familis XP_852616 248 28220 R103 S S L K Y Q T R C I R A F P N
Cat Felis silvestris
Mouse Mus musculus Q9WVA3 326 36966 S176 Y V Q Q R R E S S L K Y Q T R
Rat Rattus norvegicus Q3SWS8 368 40901 S209 S E F R R I E S P L K H Q H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512314 447 51000 S299 Y V Q Q R R E S S L K Y Q T R
Chicken Gallus gallus NP_001006506 329 37261 S179 Y V Q Q R R E S S L K Y Q T R
Frog Xenopus laevis NP_001083768 330 37234 S182 Y V Q Q R R E S S L K Y Q T R
Zebra Danio Brachydanio rerio Q7ZWF0 368 41033 S209 S E F R R I E S P L K H Q H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 T174 V S C G W D R T V K V W N L A
Honey Bee Apis mellifera XP_393536 326 36620 S176 G M F Q R R E S S L K Y Q T R
Nematode Worm Caenorhab. elegans Q93454 373 41394 E204 H I K V Y N L E N G P T E V K
Sea Urchin Strong. purpuratus XP_780636 326 36757 S177 Y V Q Q R R E S S L K Y Q T R
Poplar Tree Populus trichocarpa XP_002300265 331 36714 S176 L P E Q R R E S S L K Y Q T R
Maize Zea mays NP_001149777 343 37531 S187 Q P E Q K R D S S L K Y Q T R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38942 349 38249 S194 T E F K R I Q S P L K Y Q T R
Baker's Yeast Sacchar. cerevisiae P40066 365 40504 S205 T I F K A T T S P L K W Q T R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97 75.6 N.A. 99 33.9 N.A. 71.3 96 91.5 35.5 N.A. 20.7 64 28.9 76.8
Protein Similarity: 100 N.A. 97.3 75.6 N.A. 99 50.5 N.A. 72.2 97.8 95.7 50.8 N.A. 38.4 78 45 87.5
P-Site Identity: 100 N.A. 100 0 N.A. 100 46.6 N.A. 100 100 100 46.6 N.A. 0 80 0 100
P-Site Similarity: 100 N.A. 100 26.6 N.A. 100 60 N.A. 100 100 100 60 N.A. 13.3 86.6 40 100
Percent
Protein Identity: 54.9 51.6 N.A. 38.1 33.7 N.A.
Protein Similarity: 71.6 68.5 N.A. 56.1 49.5 N.A.
P-Site Identity: 80 66.6 N.A. 53.3 40 N.A.
P-Site Similarity: 86.6 86.6 N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 6 0 0 0 0 0 0 6 0 0 6 % A
% Cys: 0 0 6 0 0 0 0 0 6 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 6 6 0 0 0 0 0 0 0 0 % D
% Glu: 0 18 12 0 0 0 65 6 0 0 0 0 6 0 0 % E
% Phe: 0 0 30 0 0 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 6 0 0 6 0 0 0 0 0 6 0 0 0 0 0 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 12 0 12 0 % H
% Ile: 0 12 0 0 0 18 0 0 0 6 0 0 0 0 0 % I
% Lys: 0 0 6 18 6 0 0 0 0 6 83 0 0 0 6 % K
% Leu: 6 0 6 0 0 0 6 0 0 83 0 0 0 6 0 % L
% Met: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 6 0 0 6 0 0 0 6 0 6 % N
% Pro: 0 12 0 0 0 0 0 0 24 0 6 0 0 6 0 % P
% Gln: 6 0 42 59 0 6 6 0 0 0 0 0 83 0 0 % Q
% Arg: 0 0 0 12 71 59 6 6 0 0 6 0 0 0 83 % R
% Ser: 18 12 0 0 0 0 0 83 59 0 0 0 0 0 0 % S
% Thr: 12 0 0 0 0 6 12 6 0 0 0 6 0 71 0 % T
% Val: 6 42 0 6 0 0 0 0 6 0 6 0 0 6 0 % V
% Trp: 0 0 0 0 6 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 42 0 0 0 12 0 0 0 0 0 0 65 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _