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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BUB3 All Species: 29.09
Human Site: S18 Identified Species: 40
UniProt: O43684 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43684 NP_001007794.1 328 37155 S18 Q P P E D G I S S V K F S P N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105368 335 37958 S18 Q P P E D G I S S V K F S P N
Dog Lupus familis XP_852616 248 28220
Cat Felis silvestris
Mouse Mus musculus Q9WVA3 326 36966 S18 Q P P E D G I S S V K F S P N
Rat Rattus norvegicus Q3SWS8 368 40901 T51 C L S F S P P T L P G N F L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512314 447 51000 S141 E L A R D G I S S V K F S P N
Chicken Gallus gallus NP_001006506 329 37261 S21 Q T P D D G I S S V K F S P N
Frog Xenopus laevis NP_001083768 330 37234 S24 Q A P E D G I S A V K F S P N
Zebra Danio Brachydanio rerio Q7ZWF0 368 41033 T51 C L A F S P P T M P G N F L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 G16 G T L I G H N G W V T Q I A T
Honey Bee Apis mellifera XP_393536 326 36620 S18 S P P T D A I S A V E F G R N
Nematode Worm Caenorhab. elegans Q93454 373 41394 Q46 G A P E D T I Q V I K F S P T
Sea Urchin Strong. purpuratus XP_780636 326 36757 S19 Q P P E D G I S A V K F G P N
Poplar Tree Populus trichocarpa XP_002300265 331 36714 F18 D G I S N L R F S N H S D L L
Maize Zea mays NP_001149777 343 37531 F29 D G I T N L R F S N H S N N L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38942 349 38249 R36 S S L S F S P R A D I L V A T
Baker's Yeast Sacchar. cerevisiae P40066 365 40504 Q47 S D I A F S P Q Q D F M F S A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97 75.6 N.A. 99 33.9 N.A. 71.3 96 91.5 35.5 N.A. 20.7 64 28.9 76.8
Protein Similarity: 100 N.A. 97.3 75.6 N.A. 99 50.5 N.A. 72.2 97.8 95.7 50.8 N.A. 38.4 78 45 87.5
P-Site Identity: 100 N.A. 100 0 N.A. 100 0 N.A. 73.3 86.6 86.6 0 N.A. 6.6 53.3 53.3 86.6
P-Site Similarity: 100 N.A. 100 0 N.A. 100 6.6 N.A. 80 93.3 93.3 6.6 N.A. 6.6 66.6 60 93.3
Percent
Protein Identity: 54.9 51.6 N.A. 38.1 33.7 N.A.
Protein Similarity: 71.6 68.5 N.A. 56.1 49.5 N.A.
P-Site Identity: 6.6 6.6 N.A. 0 0 N.A.
P-Site Similarity: 13.3 20 N.A. 6.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 6 0 6 0 0 24 0 0 0 0 12 6 % A
% Cys: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 6 0 6 53 0 0 0 0 12 0 0 6 0 0 % D
% Glu: 6 0 0 36 0 0 0 0 0 0 6 0 0 0 0 % E
% Phe: 0 0 0 12 12 0 0 12 0 0 6 53 18 0 0 % F
% Gly: 12 12 0 0 6 42 0 6 0 0 12 0 12 0 0 % G
% His: 0 0 0 0 0 6 0 0 0 0 12 0 0 0 0 % H
% Ile: 0 0 18 6 0 0 53 0 0 6 6 0 6 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 48 0 0 0 0 % K
% Leu: 0 18 12 0 0 12 0 0 6 0 0 6 0 18 12 % L
% Met: 0 0 0 0 0 0 0 0 6 0 0 6 0 0 0 % M
% Asn: 0 0 0 0 12 0 6 0 0 12 0 12 6 6 48 % N
% Pro: 0 30 48 0 0 12 24 0 0 12 0 0 0 48 0 % P
% Gln: 36 0 0 0 0 0 0 12 6 0 0 6 0 0 0 % Q
% Arg: 0 0 0 6 0 0 12 6 0 0 0 0 0 6 0 % R
% Ser: 18 6 6 12 12 12 0 48 42 0 0 12 42 6 0 % S
% Thr: 0 12 0 12 0 6 0 12 0 0 6 0 0 0 18 % T
% Val: 0 0 0 0 0 0 0 0 6 53 0 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _