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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BUB3 All Species: 30.91
Human Site: S38 Identified Species: 42.5
UniProt: O43684 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43684 NP_001007794.1 328 37155 S38 L V S S W D T S V R L Y D V P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105368 335 37958 S38 L V S S W D T S V R L Y D V P
Dog Lupus familis XP_852616 248 28220
Cat Felis silvestris
Mouse Mus musculus Q9WVA3 326 36966 S38 L V S S W D T S V R L Y D V P
Rat Rattus norvegicus Q3SWS8 368 40901 V71 N D V R C W E V Q D S G Q T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512314 447 51000 S161 L V S S W D T S V R L Y D V P
Chicken Gallus gallus NP_001006506 329 37261 T41 L V S S W D T T V R L Y D V P
Frog Xenopus laevis NP_001083768 330 37234 S44 L V S S W D S S V R L Y D V P
Zebra Danio Brachydanio rerio Q7ZWF0 368 41033 V71 N D V R C W E V Q D N G Q T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 R36 D T I I S A S R D K T L I V W
Honey Bee Apis mellifera XP_393536 326 36620 T38 L V S S W D S T V R L Y D I H
Nematode Worm Caenorhab. elegans Q93454 373 41394 D66 M L A C G S W D G T I R V W M
Sea Urchin Strong. purpuratus XP_780636 326 36757 T39 L V S S W D E T V R L Y D V Q
Poplar Tree Populus trichocarpa XP_002300265 331 36714 D38 D K T V R L Y D A S A N A L R
Maize Zea mays NP_001149777 343 37531 D49 D K T V R L Y D A D A N V L K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38942 349 38249 R56 V R C W E I S R S G A S L A S
Baker's Yeast Sacchar. cerevisiae P40066 365 40504 Q67 K V R I W D V Q N G V P Q G R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97 75.6 N.A. 99 33.9 N.A. 71.3 96 91.5 35.5 N.A. 20.7 64 28.9 76.8
Protein Similarity: 100 N.A. 97.3 75.6 N.A. 99 50.5 N.A. 72.2 97.8 95.7 50.8 N.A. 38.4 78 45 87.5
P-Site Identity: 100 N.A. 100 0 N.A. 100 0 N.A. 100 93.3 93.3 0 N.A. 6.6 73.3 0 80
P-Site Similarity: 100 N.A. 100 0 N.A. 100 0 N.A. 100 100 100 0 N.A. 20 93.3 26.6 86.6
Percent
Protein Identity: 54.9 51.6 N.A. 38.1 33.7 N.A.
Protein Similarity: 71.6 68.5 N.A. 56.1 49.5 N.A.
P-Site Identity: 0 0 N.A. 0 20 N.A.
P-Site Similarity: 13.3 13.3 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 0 0 6 0 0 12 0 18 0 6 6 0 % A
% Cys: 0 0 6 6 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 18 12 0 0 0 53 0 18 6 18 0 0 48 0 0 % D
% Glu: 0 0 0 0 6 0 18 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 6 0 0 0 6 12 0 12 0 6 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % H
% Ile: 0 0 6 12 0 6 0 0 0 0 6 0 6 6 6 % I
% Lys: 6 12 0 0 0 0 0 0 0 6 0 0 0 0 6 % K
% Leu: 48 6 0 0 0 12 0 0 0 0 48 6 6 12 0 % L
% Met: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % M
% Asn: 12 0 0 0 0 0 0 0 6 0 6 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 36 % P
% Gln: 0 0 0 0 0 0 0 6 12 0 0 0 18 0 6 % Q
% Arg: 0 6 6 12 12 0 0 12 0 48 0 6 0 0 12 % R
% Ser: 0 0 48 48 6 6 24 30 6 6 6 6 0 0 6 % S
% Thr: 0 6 12 0 0 0 30 18 0 6 6 0 0 12 0 % T
% Val: 6 53 12 12 0 0 6 12 48 0 6 0 12 48 6 % V
% Trp: 0 0 0 6 53 12 6 0 0 0 0 0 0 6 6 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 0 48 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _