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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BUB3 All Species: 48.48
Human Site: T154 Identified Species: 66.67
UniProt: O43684 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43684 NP_001007794.1 328 37155 T154 G D R L I V G T A G R R V L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105368 335 37958 T154 G D R L I V G T A G R R V L V
Dog Lupus familis XP_852616 248 28220 V81 T A G R R V L V W D L R N M G
Cat Felis silvestris
Mouse Mus musculus Q9WVA3 326 36966 T154 G D R L I V G T A G R R V L V
Rat Rattus norvegicus Q3SWS8 368 40901 T187 Y P M A V V A T A E R G L I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512314 447 51000 T277 G D R L I V G T A G R R V L V
Chicken Gallus gallus NP_001006506 329 37261 T157 G D R L I V G T A G R R V L V
Frog Xenopus laevis NP_001083768 330 37234 T160 G D R L I V G T A G R R V L V
Zebra Danio Brachydanio rerio Q7ZWF0 368 41033 T187 Y P M A V V A T A E R G L I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 V152 E D G H T D W V S C V R F S P
Honey Bee Apis mellifera XP_393536 326 36620 T154 G D K F V V G T A K R K V C I
Nematode Worm Caenorhab. elegans Q93454 373 41394 A182 L P E R V Y A A D V L Y P M A
Sea Urchin Strong. purpuratus XP_780636 326 36757 T155 G D R L V V G T A G R K V L V
Poplar Tree Populus trichocarpa XP_002300265 331 36714 T154 G N R L V V A T A G R H V N V
Maize Zea mays NP_001149777 343 37531 T165 G N R L V V A T A G R H V N I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38942 349 38249 T172 H P L M V V G T A D R N L I V
Baker's Yeast Sacchar. cerevisiae P40066 365 40504 T183 Q S L L V V A T A E R H I A I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97 75.6 N.A. 99 33.9 N.A. 71.3 96 91.5 35.5 N.A. 20.7 64 28.9 76.8
Protein Similarity: 100 N.A. 97.3 75.6 N.A. 99 50.5 N.A. 72.2 97.8 95.7 50.8 N.A. 38.4 78 45 87.5
P-Site Identity: 100 N.A. 100 13.3 N.A. 100 33.3 N.A. 100 100 100 33.3 N.A. 13.3 53.3 0 86.6
P-Site Similarity: 100 N.A. 100 20 N.A. 100 53.3 N.A. 100 100 100 53.3 N.A. 20 80 13.3 100
Percent
Protein Identity: 54.9 51.6 N.A. 38.1 33.7 N.A.
Protein Similarity: 71.6 68.5 N.A. 56.1 49.5 N.A.
P-Site Identity: 66.6 60 N.A. 40 33.3 N.A.
P-Site Similarity: 80 80 N.A. 66.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 12 0 0 36 6 83 0 0 0 0 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 6 0 0 0 6 0 % C
% Asp: 0 53 0 0 0 6 0 0 6 12 0 0 0 0 0 % D
% Glu: 6 0 6 0 0 0 0 0 0 18 0 0 0 0 0 % E
% Phe: 0 0 0 6 0 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 59 0 12 0 0 0 53 0 0 53 0 12 0 0 6 % G
% His: 6 0 0 6 0 0 0 0 0 0 0 18 0 0 0 % H
% Ile: 0 0 0 0 36 0 0 0 0 0 0 0 6 18 18 % I
% Lys: 0 0 6 0 0 0 0 0 0 6 0 12 0 0 0 % K
% Leu: 6 0 12 59 0 0 6 0 0 0 12 0 18 42 0 % L
% Met: 0 0 12 6 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 0 0 6 6 12 0 % N
% Pro: 0 24 0 0 0 0 0 0 0 0 0 0 6 0 6 % P
% Gln: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 53 12 6 0 0 0 0 0 83 48 0 0 0 % R
% Ser: 0 6 0 0 0 0 0 0 6 0 0 0 0 6 0 % S
% Thr: 6 0 0 0 6 0 0 83 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 53 89 0 12 0 6 6 0 59 0 65 % V
% Trp: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 6 0 0 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _