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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BUB3 All Species: 36.97
Human Site: Y169 Identified Species: 50.83
UniProt: O43684 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43684 NP_001007794.1 328 37155 Y169 W D L R N M G Y V Q Q R R E S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105368 335 37958 Y169 W D L R N M G Y V Q Q R R E S
Dog Lupus familis XP_852616 248 28220 S96 Y V Q Q R R E S S L K Y Q T R
Cat Felis silvestris
Mouse Mus musculus Q9WVA3 326 36966 Y169 W D L W N M G Y V Q Q R R E S
Rat Rattus norvegicus Q3SWS8 368 40901 S202 Y Q L E N Q P S E F R R I E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512314 447 51000 Y292 W D L R N M G Y V Q Q R R E S
Chicken Gallus gallus NP_001006506 329 37261 Y172 W D L R N M G Y V Q Q R R E S
Frog Xenopus laevis NP_001083768 330 37234 Y175 W D L R N M G Y V Q Q R R E S
Zebra Danio Brachydanio rerio Q7ZWF0 368 41033 S202 Y Q L E N Q P S E F R R I E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 V167 N H S N P I I V S C G W D R T
Honey Bee Apis mellifera XP_393536 326 36620 G169 W D L R N M A G M F Q R R E S
Nematode Worm Caenorhab. elegans Q93454 373 41394 H197 V V A L A N K H I K V Y N L E
Sea Urchin Strong. purpuratus XP_780636 326 36757 Y170 W D L R N M G Y V Q Q R R E S
Poplar Tree Populus trichocarpa XP_002300265 331 36714 L169 Y D L R N M S L P E Q R R E S
Maize Zea mays NP_001149777 343 37531 Q180 Y D L R N M S Q P E Q K R D S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38942 349 38249 T187 F N L Q N P Q T E F K R I Q S
Baker's Yeast Sacchar. cerevisiae P40066 365 40504 T198 I N L A N P T T I F K A T T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97 75.6 N.A. 99 33.9 N.A. 71.3 96 91.5 35.5 N.A. 20.7 64 28.9 76.8
Protein Similarity: 100 N.A. 97.3 75.6 N.A. 99 50.5 N.A. 72.2 97.8 95.7 50.8 N.A. 38.4 78 45 87.5
P-Site Identity: 100 N.A. 100 0 N.A. 93.3 33.3 N.A. 100 100 100 33.3 N.A. 0 73.3 0 100
P-Site Similarity: 100 N.A. 100 26.6 N.A. 93.3 46.6 N.A. 100 100 100 46.6 N.A. 13.3 80 20 100
Percent
Protein Identity: 54.9 51.6 N.A. 38.1 33.7 N.A.
Protein Similarity: 71.6 68.5 N.A. 56.1 49.5 N.A.
P-Site Identity: 66.6 53.3 N.A. 26.6 20 N.A.
P-Site Similarity: 80 80 N.A. 60 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 6 6 0 6 0 0 0 0 6 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 0 59 0 0 0 0 0 0 0 0 0 0 6 6 0 % D
% Glu: 0 0 0 12 0 0 6 0 18 12 0 0 0 65 6 % E
% Phe: 6 0 0 0 0 0 0 0 0 30 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 42 6 0 0 6 0 0 0 0 % G
% His: 0 6 0 0 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 6 0 0 0 0 6 6 0 12 0 0 0 18 0 0 % I
% Lys: 0 0 0 0 0 0 6 0 0 6 18 6 0 0 0 % K
% Leu: 0 0 83 6 0 0 0 6 0 6 0 0 0 6 0 % L
% Met: 0 0 0 0 0 59 0 0 6 0 0 0 0 0 0 % M
% Asn: 6 12 0 6 83 6 0 0 0 0 0 0 6 0 0 % N
% Pro: 0 0 0 0 6 12 12 0 12 0 0 0 0 0 0 % P
% Gln: 0 12 6 12 0 12 6 6 0 42 59 0 6 6 0 % Q
% Arg: 0 0 0 53 6 6 0 0 0 0 12 71 59 6 6 % R
% Ser: 0 0 6 0 0 0 12 18 12 0 0 0 0 0 83 % S
% Thr: 0 0 0 0 0 0 6 12 0 0 0 0 6 12 6 % T
% Val: 6 12 0 0 0 0 0 6 42 0 6 0 0 0 0 % V
% Trp: 48 0 0 6 0 0 0 0 0 0 0 6 0 0 0 % W
% Tyr: 30 0 0 0 0 0 0 42 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _