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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BUB3 All Species: 45.15
Human Site: Y180 Identified Species: 62.08
UniProt: O43684 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43684 NP_001007794.1 328 37155 Y180 R R E S S L K Y Q T R C I R A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105368 335 37958 Y180 R R E S S L K Y Q T R C I R A
Dog Lupus familis XP_852616 248 28220 A107 Y Q T R C I R A F P N K Q G Y
Cat Felis silvestris
Mouse Mus musculus Q9WVA3 326 36966 Y180 R R E S S L K Y Q T R C I R A
Rat Rattus norvegicus Q3SWS8 368 40901 H213 R I E S P L K H Q H R C V A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512314 447 51000 Y303 R R E S S L K Y Q T R C I R A
Chicken Gallus gallus NP_001006506 329 37261 Y183 R R E S S L K Y Q T R C I R A
Frog Xenopus laevis NP_001083768 330 37234 Y186 R R E S S L K Y Q T R C I R A
Zebra Danio Brachydanio rerio Q7ZWF0 368 41033 H213 R I E S P L K H Q H R C V A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18640 318 35599 W178 W D R T V K V W N L A N C K L
Honey Bee Apis mellifera XP_393536 326 36620 Y180 R R E S S L K Y Q T R C I K G
Nematode Worm Caenorhab. elegans Q93454 373 41394 T208 Y N L E N G P T E V K D I E S
Sea Urchin Strong. purpuratus XP_780636 326 36757 Y181 R R E S S L K Y Q T R C I R S
Poplar Tree Populus trichocarpa XP_002300265 331 36714 Y180 R R E S S L K Y Q T R C V R C
Maize Zea mays NP_001149777 343 37531 Y191 K R D S S L K Y Q T R C V R C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38942 349 38249 Y198 R I Q S P L K Y Q T R C V T A
Baker's Yeast Sacchar. cerevisiae P40066 365 40504 W209 A T T S P L K W Q T R C V A C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97 75.6 N.A. 99 33.9 N.A. 71.3 96 91.5 35.5 N.A. 20.7 64 28.9 76.8
Protein Similarity: 100 N.A. 97.3 75.6 N.A. 99 50.5 N.A. 72.2 97.8 95.7 50.8 N.A. 38.4 78 45 87.5
P-Site Identity: 100 N.A. 100 0 N.A. 100 53.3 N.A. 100 100 100 53.3 N.A. 0 86.6 6.6 93.3
P-Site Similarity: 100 N.A. 100 20 N.A. 100 66.6 N.A. 100 100 100 66.6 N.A. 20 93.3 33.3 100
Percent
Protein Identity: 54.9 51.6 N.A. 38.1 33.7 N.A.
Protein Similarity: 71.6 68.5 N.A. 56.1 49.5 N.A.
P-Site Identity: 86.6 73.3 N.A. 66.6 46.6 N.A.
P-Site Similarity: 93.3 93.3 N.A. 80 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 0 0 0 6 0 0 6 0 0 18 42 % A
% Cys: 0 0 0 0 6 0 0 0 0 0 0 83 6 0 18 % C
% Asp: 0 6 6 0 0 0 0 0 0 0 0 6 0 0 0 % D
% Glu: 0 0 65 6 0 0 0 0 6 0 0 0 0 6 0 % E
% Phe: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 6 0 0 0 0 0 0 0 6 6 % G
% His: 0 0 0 0 0 0 0 12 0 12 0 0 0 0 0 % H
% Ile: 0 18 0 0 0 6 0 0 0 0 0 0 53 0 12 % I
% Lys: 6 0 0 0 0 6 83 0 0 0 6 6 0 12 0 % K
% Leu: 0 0 6 0 0 83 0 0 0 6 0 0 0 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 6 0 0 0 6 0 6 6 0 0 0 % N
% Pro: 0 0 0 0 24 0 6 0 0 6 0 0 0 0 0 % P
% Gln: 0 6 6 0 0 0 0 0 83 0 0 0 6 0 0 % Q
% Arg: 71 59 6 6 0 0 6 0 0 0 83 0 0 53 0 % R
% Ser: 0 0 0 83 59 0 0 0 0 0 0 0 0 0 12 % S
% Thr: 0 6 12 6 0 0 0 6 0 71 0 0 0 6 0 % T
% Val: 0 0 0 0 6 0 6 0 0 6 0 0 36 0 0 % V
% Trp: 6 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 0 65 0 0 0 0 0 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _