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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2C
All Species:
24.55
Human Site:
S163
Identified Species:
45
UniProt:
O43688
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43688
NP_003703.1
288
32574
S163
D
V
T
E
A
R
L
S
F
Y
S
G
H
S
S
Chimpanzee
Pan troglodytes
XP_517759
284
32152
S166
R
V
K
E
G
R
L
S
F
Y
S
G
H
S
S
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
S163
D
V
T
E
A
R
L
S
F
Y
S
G
H
S
S
Dog
Lupus familis
XP_855263
379
41875
S254
N
V
T
E
S
R
L
S
F
Y
S
G
H
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAX2
276
31175
R160
P
A
N
V
T
E
A
R
L
S
F
Y
S
G
H
Rat
Rattus norvegicus
Q8K593
276
31083
R160
P
A
N
V
T
E
A
R
L
S
F
Y
S
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424730
246
27534
L131
G
R
L
R
P
H
F
L
A
V
C
Q
P
D
W
Frog
Xenopus laevis
Q6GM05
314
34960
T188
L
V
I
K
A
R
R
T
F
P
S
K
D
A
A
Zebra Danio
Brachydanio rerio
XP_692261
365
41538
M203
S
G
H
S
S
F
G
M
Y
C
M
L
F
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
K243
D
D
A
I
N
A
G
K
Y
I
Q
E
F
T
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
S192
L
V
L
E
A
R
K
S
F
Y
S
G
H
S
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU49
327
36665
S186
E
V
K
E
G
H
K
S
F
P
S
G
H
T
S
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
T164
R
L
L
D
G
F
R
T
T
P
S
G
H
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.9
91
69.1
N.A.
86.8
87.5
N.A.
N.A.
50.6
26.1
53.9
N.A.
31.6
N.A.
30.7
N.A.
Protein Similarity:
100
71.8
93.7
72.5
N.A.
92
92.3
N.A.
N.A.
67.7
47.1
65.4
N.A.
47.2
N.A.
46.9
N.A.
P-Site Identity:
100
80
100
86.6
N.A.
0
0
N.A.
N.A.
0
33.3
0
N.A.
6.6
N.A.
73.3
N.A.
P-Site Similarity:
100
80
100
100
N.A.
0
0
N.A.
N.A.
0
60
20
N.A.
20
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
31
8
16
0
8
0
0
0
0
8
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% C
% Asp:
24
8
0
8
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
8
0
0
47
0
16
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
16
8
0
54
0
16
0
16
0
0
% F
% Gly:
8
8
0
0
24
0
16
0
0
0
0
54
0
16
0
% G
% His:
0
0
8
0
0
16
0
0
0
0
0
0
54
0
16
% H
% Ile:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
16
8
0
0
16
8
0
0
0
8
0
0
0
% K
% Leu:
16
8
24
0
0
0
31
8
16
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
8
0
16
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
16
0
0
0
8
0
0
0
0
24
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
16
8
0
8
0
47
16
16
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
16
0
0
47
0
16
62
0
16
47
47
% S
% Thr:
0
0
24
0
16
0
0
16
8
0
0
0
0
16
0
% T
% Val:
0
54
0
16
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
16
39
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _