KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2C
All Species:
4.55
Human Site:
S288
Identified Species:
8.33
UniProt:
O43688
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43688
NP_003703.1
288
32574
S288
Y
G
Y
P
H
S
S
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_517759
284
32152
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
Dog
Lupus familis
XP_855263
379
41875
S379
Y
G
Y
P
V
S
S
S
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAX2
276
31175
P276
T
L
T
L
G
D
R
P
_
_
_
_
_
_
_
Rat
Rattus norvegicus
Q8K593
276
31083
P276
T
L
T
L
G
D
R
P
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424730
246
27534
Frog
Xenopus laevis
Q6GM05
314
34960
T314
L
T
A
F
A
E
V
T
_
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
XP_692261
365
41538
V344
H
L
T
P
N
D
T
V
F
I
V
S
E
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
D331
A
T
G
P
Q
D
S
D
T
I
L
L
P
V
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU49
327
36665
R327
S
G
T
S
T
A
P
R
_
_
_
_
_
_
_
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.9
91
69.1
N.A.
86.8
87.5
N.A.
N.A.
50.6
26.1
53.9
N.A.
31.6
N.A.
30.7
N.A.
Protein Similarity:
100
71.8
93.7
72.5
N.A.
92
92.3
N.A.
N.A.
67.7
47.1
65.4
N.A.
47.2
N.A.
46.9
N.A.
P-Site Identity:
100
0
0
87.5
N.A.
0
0
N.A.
N.A.
0
0
6.6
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
0
0
87.5
N.A.
0
0
N.A.
N.A.
0
12.5
33.3
N.A.
0
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
12.5
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
25
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
31
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
24
8
0
16
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
8
24
0
16
0
0
0
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
31
0
0
8
16
0
0
0
0
8
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
16
24
16
0
0
0
8
0
0
0
% S
% Thr:
16
16
31
0
8
0
8
8
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
8
8
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
47
47
47
47
47
47
47
% _