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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2C
All Species:
13.64
Human Site:
T270
Identified Species:
25
UniProt:
O43688
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43688
NP_003703.1
288
32574
T270
R
K
P
S
L
S
L
T
L
T
L
G
E
A
D
Chimpanzee
Pan troglodytes
XP_517759
284
32152
T267
K
E
E
D
S
H
T
T
L
H
E
T
P
T
T
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
T272
R
K
P
S
L
S
L
T
L
T
L
G
E
A
D
Dog
Lupus familis
XP_855263
379
41875
T361
R
K
P
S
L
S
L
T
L
T
L
G
E
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAX2
276
31175
E258
P
Q
P
C
Q
E
D
E
V
P
E
R
K
P
S
Rat
Rattus norvegicus
Q8K593
276
31083
E258
P
Q
S
C
Q
E
N
E
E
S
E
R
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424730
246
27534
L229
K
H
H
W
S
D
V
L
T
G
L
I
Q
G
A
Frog
Xenopus laevis
Q6GM05
314
34960
P296
Q
M
P
I
I
S
I
P
R
V
E
N
P
L
E
Zebra Danio
Brachydanio rerio
XP_692261
365
41538
F326
R
L
Y
R
L
S
L
F
C
T
L
I
Y
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
T362
T
K
P
Y
L
A
R
T
V
Q
D
M
N
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
L313
R
H
R
L
D
A
V
L
P
S
T
D
S
S
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU49
327
36665
Q309
A
L
R
A
M
S
L
Q
M
D
S
T
S
L
E
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
T272
V
T
L
E
E
A
V
T
H
Q
R
I
P
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.9
91
69.1
N.A.
86.8
87.5
N.A.
N.A.
50.6
26.1
53.9
N.A.
31.6
N.A.
30.7
N.A.
Protein Similarity:
100
71.8
93.7
72.5
N.A.
92
92.3
N.A.
N.A.
67.7
47.1
65.4
N.A.
47.2
N.A.
46.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
6.6
0
N.A.
N.A.
6.6
13.3
40
N.A.
33.3
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
26.6
20
N.A.
N.A.
26.6
40
46.6
N.A.
46.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
24
0
0
0
0
0
0
0
31
8
% A
% Cys:
0
0
0
16
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
8
8
0
0
8
8
8
0
8
24
% D
% Glu:
0
8
8
8
8
16
0
16
8
0
31
0
24
0
24
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
24
0
8
0
% G
% His:
0
16
8
0
0
8
0
0
8
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
8
0
0
0
0
24
0
0
8
% I
% Lys:
16
31
0
0
0
0
0
0
0
0
0
0
16
0
8
% K
% Leu:
0
16
8
8
39
0
39
16
31
0
39
0
0
16
0
% L
% Met:
0
8
0
0
8
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% N
% Pro:
16
0
47
0
0
0
0
8
8
8
0
0
24
16
0
% P
% Gln:
8
16
0
0
16
0
0
8
0
16
0
0
8
0
0
% Q
% Arg:
39
0
16
8
0
0
8
0
8
0
8
16
0
0
0
% R
% Ser:
0
0
8
24
16
47
0
0
0
16
8
0
16
16
24
% S
% Thr:
8
8
0
0
0
0
8
47
8
31
8
16
0
8
8
% T
% Val:
8
0
0
0
0
0
24
0
16
8
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _