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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2C
All Species:
22.42
Human Site:
Y118
Identified Species:
41.11
UniProt:
O43688
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43688
NP_003703.1
288
32574
Y118
S
L
T
D
L
A
K
Y
M
I
G
R
L
R
P
Chimpanzee
Pan troglodytes
XP_517759
284
32152
K120
Q
S
L
T
D
I
A
K
Y
S
I
G
R
L
R
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
Y118
S
L
T
D
L
A
K
Y
M
I
G
R
L
R
P
Dog
Lupus familis
XP_855263
379
41875
Y209
S
L
T
D
L
A
K
Y
M
I
G
R
L
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAX2
276
31175
Y118
S
L
T
D
L
A
K
Y
M
I
G
R
L
R
P
Rat
Rattus norvegicus
Q8K593
276
31083
Y118
S
L
T
D
L
A
K
Y
M
I
G
R
L
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424730
246
27534
F89
N
H
L
H
S
N
S
F
V
R
N
N
Y
I
A
Frog
Xenopus laevis
Q6GM05
314
34960
L113
D
C
C
Y
I
N
P
L
V
R
R
T
V
R
F
Zebra Danio
Brachydanio rerio
XP_692261
365
41538
Y153
S
L
T
D
M
A
K
Y
T
I
G
R
L
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
A200
I
G
I
Y
A
F
G
A
V
L
S
Q
L
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
I137
Q
I
G
F
V
M
N
I
A
L
N
I
V
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU49
327
36665
V144
V
I
T
D
S
I
K
V
A
T
G
R
P
R
P
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
N119
F
F
T
N
F
I
K
N
W
I
G
R
L
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.9
91
69.1
N.A.
86.8
87.5
N.A.
N.A.
50.6
26.1
53.9
N.A.
31.6
N.A.
30.7
N.A.
Protein Similarity:
100
71.8
93.7
72.5
N.A.
92
92.3
N.A.
N.A.
67.7
47.1
65.4
N.A.
47.2
N.A.
46.9
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
0
6.6
86.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
20
26.6
93.3
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
47
8
8
16
0
0
0
0
0
8
% A
% Cys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
54
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
8
8
8
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
0
0
0
8
0
0
0
62
8
0
0
0
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
8
0
8
24
0
8
0
54
8
8
0
8
0
% I
% Lys:
0
0
0
0
0
0
62
8
0
0
0
0
0
0
8
% K
% Leu:
0
47
16
0
39
0
0
8
0
16
0
0
62
8
0
% L
% Met:
0
0
0
0
8
8
0
0
39
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
16
8
8
0
0
16
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
62
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
16
8
62
8
70
8
% R
% Ser:
47
8
0
0
16
0
8
0
0
8
8
0
0
0
0
% S
% Thr:
0
0
62
8
0
0
0
0
8
8
0
8
0
16
8
% T
% Val:
8
0
0
0
8
0
0
8
24
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
47
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _