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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPAP2C All Species: 10.91
Human Site: Y212 Identified Species: 20
UniProt: O43688 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43688 NP_003703.1 288 32574 Y212 A F A L Y V G Y T R V S D Y K
Chimpanzee Pan troglodytes XP_517759 284 32152 L215 A V S I Y V G L S R V S D Y K
Rhesus Macaque Macaca mulatta XP_001116998 289 31981 Y214 A F A L Y V G Y T R V S D Y K
Dog Lupus familis XP_855263 379 41875 Y303 A F A L Y V G Y T R V S D H K
Cat Felis silvestris
Mouse Mus musculus Q9DAX2 276 31175 Y208 F L V A F A I Y V G Y T R V S
Rat Rattus norvegicus Q8K593 276 31083 Y208 F L V A F A I Y V G Y T R V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424730 246 27534 M179 S S F S M Y C M L F L A L Y L
Frog Xenopus laevis Q6GM05 314 34960 I237 C L A F L T G I N R V A E Y R
Zebra Danio Brachydanio rerio XP_692261 365 41538 I273 A V L T V R Y I S D F F K E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V576 379 42771 W292 Y L Q A R M T W R G S K L L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10022 341 39009 F242 M I G L G I S F S R I T D N K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZU49 327 36665 I237 L A A C L V G I S R V D D Y W
Baker's Yeast Sacchar. cerevisiae Q05521 289 33495 L215 L G A A L I A L S R T Q D Y R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.9 91 69.1 N.A. 86.8 87.5 N.A. N.A. 50.6 26.1 53.9 N.A. 31.6 N.A. 30.7 N.A.
Protein Similarity: 100 71.8 93.7 72.5 N.A. 92 92.3 N.A. N.A. 67.7 47.1 65.4 N.A. 47.2 N.A. 46.9 N.A.
P-Site Identity: 100 66.6 100 93.3 N.A. 6.6 6.6 N.A. N.A. 6.6 33.3 6.6 N.A. 0 N.A. 26.6 N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 20 20 N.A. N.A. 26.6 53.3 20 N.A. 20 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.8 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. 39.4 38.7 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 8 47 31 0 16 8 0 0 0 0 16 0 0 0 % A
% Cys: 8 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 8 54 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % E
% Phe: 16 24 8 8 16 0 0 8 0 8 8 8 0 0 0 % F
% Gly: 0 8 8 0 8 0 47 0 0 24 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 8 0 16 16 24 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 39 % K
% Leu: 16 31 8 31 24 0 0 16 8 0 8 0 16 8 8 % L
% Met: 8 0 0 0 8 8 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 8 8 0 0 8 62 0 0 16 0 31 % R
% Ser: 8 8 8 8 0 0 8 0 39 0 8 31 0 0 16 % S
% Thr: 0 0 0 8 0 8 8 0 24 0 8 24 0 0 0 % T
% Val: 0 16 16 0 8 39 0 0 16 0 47 0 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % W
% Tyr: 8 0 0 0 31 8 8 39 0 0 16 0 0 54 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _