KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2C
All Species:
20
Human Site:
Y218
Identified Species:
36.67
UniProt:
O43688
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43688
NP_003703.1
288
32574
Y218
G
Y
T
R
V
S
D
Y
K
H
H
W
S
D
V
Chimpanzee
Pan troglodytes
XP_517759
284
32152
Y221
G
L
S
R
V
S
D
Y
K
H
H
W
S
D
V
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
Y220
G
Y
T
R
V
S
D
Y
K
H
H
W
S
D
V
Dog
Lupus familis
XP_855263
379
41875
H309
G
Y
T
R
V
S
D
H
K
H
H
W
S
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAX2
276
31175
V214
I
Y
V
G
Y
T
R
V
S
D
H
K
H
H
W
Rat
Rattus norvegicus
Q8K593
276
31083
V214
I
Y
V
G
Y
T
R
V
S
D
N
K
H
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424730
246
27534
Y185
C
M
L
F
L
A
L
Y
L
Q
A
R
M
K
G
Frog
Xenopus laevis
Q6GM05
314
34960
Y243
G
I
N
R
V
A
E
Y
R
N
H
W
S
D
V
Zebra Danio
Brachydanio rerio
XP_692261
365
41538
E279
Y
I
S
D
F
F
K
E
R
P
P
R
C
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
L298
T
W
R
G
S
K
L
L
R
H
L
L
Q
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
N248
S
F
S
R
I
T
D
N
K
H
H
W
S
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU49
327
36665
Y243
G
I
S
R
V
D
D
Y
W
H
H
W
Q
D
V
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
Y221
A
L
S
R
T
Q
D
Y
R
H
H
F
V
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.9
91
69.1
N.A.
86.8
87.5
N.A.
N.A.
50.6
26.1
53.9
N.A.
31.6
N.A.
30.7
N.A.
Protein Similarity:
100
71.8
93.7
72.5
N.A.
92
92.3
N.A.
N.A.
67.7
47.1
65.4
N.A.
47.2
N.A.
46.9
N.A.
P-Site Identity:
100
86.6
100
93.3
N.A.
13.3
6.6
N.A.
N.A.
6.6
60
0
N.A.
6.6
N.A.
60
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
20
20
N.A.
N.A.
20
86.6
13.3
N.A.
26.6
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
0
0
0
0
8
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
8
54
0
0
16
0
0
0
62
8
% D
% Glu:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
8
8
8
0
0
0
0
0
8
0
8
0
% F
% Gly:
47
0
0
24
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
62
70
0
16
16
0
% H
% Ile:
16
24
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
8
0
39
0
0
16
0
8
0
% K
% Leu:
0
16
8
0
8
0
16
8
8
0
8
8
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
0
16
0
0
% Q
% Arg:
0
0
8
62
0
0
16
0
31
0
0
16
0
0
0
% R
% Ser:
8
0
39
0
8
31
0
0
16
0
0
0
47
0
0
% S
% Thr:
8
0
24
0
8
24
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
16
0
47
0
0
16
0
0
0
0
8
0
62
% V
% Trp:
0
8
0
0
0
0
0
0
8
0
0
54
0
0
16
% W
% Tyr:
8
39
0
0
16
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _