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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WBSCR22
All Species:
8.48
Human Site:
S248
Identified Species:
14.36
UniProt:
O43709
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43709
NP_059998.2
281
31880
S248
R
R
G
M
V
R
K
S
R
A
W
V
L
E
K
Chimpanzee
Pan troglodytes
XP_001146333
288
32424
S255
R
R
G
M
V
R
K
S
R
A
W
V
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001115175
244
26972
N219
I
P
E
G
L
S
E
N
Q
D
E
D
E
P
R
Dog
Lupus familis
XP_536843
284
32044
V248
R
I
A
C
R
G
V
V
R
K
S
R
E
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY21
281
31568
S248
R
R
D
L
V
K
K
S
R
E
W
V
L
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034421
282
31481
K248
A
K
G
K
S
V
K
K
S
R
D
W
I
L
E
Frog
Xenopus laevis
NP_001085369
282
31627
K248
T
R
G
K
S
A
K
K
S
K
D
W
I
L
E
Zebra Danio
Brachydanio rerio
NP_001076348
282
31663
K248
M
K
G
K
S
A
K
K
S
K
D
W
I
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649762
276
31107
W246
A
P
K
K
S
R
D
W
I
L
A
K
K
E
R
Honey Bee
Apis mellifera
XP_623810
275
31197
W245
S
L
K
N
S
R
N
W
I
M
E
K
K
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786791
283
31707
K247
M
K
G
K
S
V
K
K
S
R
E
W
I
K
E
Poplar Tree
Populus trichocarpa
XP_002300071
289
32108
K246
S
D
R
N
R
P
K
K
K
Q
K
I
T
R
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200538
289
32368
K246
S
D
R
N
R
P
R
K
R
Q
R
T
N
T
K
Baker's Yeast
Sacchar. cerevisiae
P25627
275
30724
K243
G
K
D
K
E
S
A
K
S
F
I
L
R
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
84.6
82.7
N.A.
79.7
N.A.
N.A.
N.A.
69.8
66.3
65.9
N.A.
59.7
58.7
N.A.
59.3
Protein Similarity:
100
94.4
84.6
91.9
N.A.
91.4
N.A.
N.A.
N.A.
83.3
85.1
83.6
N.A.
75
77.5
N.A.
77.3
P-Site Identity:
100
100
0
13.3
N.A.
73.3
N.A.
N.A.
N.A.
13.3
20
13.3
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
33.3
13.3
N.A.
86.6
N.A.
N.A.
N.A.
33.3
33.3
26.6
N.A.
20
20
N.A.
40
Percent
Protein Identity:
54.3
N.A.
N.A.
52.6
48
N.A.
Protein Similarity:
69.9
N.A.
N.A.
68.8
68.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
0
0
15
8
0
0
15
8
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
15
0
0
0
8
0
0
8
22
8
0
0
8
% D
% Glu:
0
0
8
0
8
0
8
0
0
8
22
0
15
36
22
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
43
8
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
15
0
8
8
29
0
0
% I
% Lys:
0
29
15
43
0
8
58
50
8
22
8
15
15
15
43
% K
% Leu:
0
8
0
8
8
0
0
0
0
8
0
8
22
22
0
% L
% Met:
15
0
0
15
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
22
0
0
8
8
0
0
0
0
8
0
0
% N
% Pro:
0
15
0
0
0
15
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
15
0
0
0
0
0
% Q
% Arg:
29
29
15
0
22
29
8
0
36
15
8
8
8
8
22
% R
% Ser:
22
0
0
0
43
15
0
22
36
0
8
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% T
% Val:
0
0
0
0
22
15
8
8
0
0
0
22
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
15
0
0
22
29
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _