Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WBSCR22 All Species: 25.76
Human Site: S30 Identified Species: 43.59
UniProt: O43709 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43709 NP_059998.2 281 31880 S30 A R K Y V R N S R M I D I Q T
Chimpanzee Pan troglodytes XP_001146333 288 32424 S30 A R K Y V R N S R M I D I Q T
Rhesus Macaque Macaca mulatta XP_001115175 244 26972 F17 H G G P P E L F Y D E K E A R
Dog Lupus familis XP_536843 284 32044 S30 A R K Y V R N S R M I D V Q T
Cat Felis silvestris
Mouse Mus musculus Q9CY21 281 31568 S30 A R K Y V R N S R M I D I Q T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034421 282 31481 S30 A R K Y T Q N S R V A E I Q A
Frog Xenopus laevis NP_001085369 282 31627 S30 A R K Y T Q N S R M I E I Q T
Zebra Danio Brachydanio rerio NP_001076348 282 31663 S30 A K K Y S Q N S R M I E I Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649762 276 31107 I30 Y S T N T R I I E I Q V E M A
Honey Bee Apis mellifera XP_623810 275 31197 I30 Y T Q N S R M I D I Q E Q M C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786791 283 31707 R30 R K Y T S N T R M I E I Q M T
Poplar Tree Populus trichocarpa XP_002300071 289 32108 I30 Y T S S S R I I D I Q A R L S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200538 289 32368 V30 Y T S S S R I V E I Q A K L S
Baker's Yeast Sacchar. cerevisiae P25627 275 30724 K34 R V Q H I Q A K M T L R A L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 84.6 82.7 N.A. 79.7 N.A. N.A. N.A. 69.8 66.3 65.9 N.A. 59.7 58.7 N.A. 59.3
Protein Similarity: 100 94.4 84.6 91.9 N.A. 91.4 N.A. N.A. N.A. 83.3 85.1 83.6 N.A. 75 77.5 N.A. 77.3
P-Site Identity: 100 100 0 93.3 N.A. 100 N.A. N.A. N.A. 60 80 73.3 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 0 100 N.A. 100 N.A. N.A. N.A. 80 93.3 93.3 N.A. 13.3 26.6 N.A. 20
Percent
Protein Identity: 54.3 N.A. N.A. 52.6 48 N.A.
Protein Similarity: 69.9 N.A. N.A. 68.8 68.3 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 20 N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 0 0 8 0 0 0 8 15 8 8 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 15 8 0 29 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 15 0 15 29 15 0 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 22 22 0 36 43 8 43 0 0 % I
% Lys: 0 15 50 0 0 0 0 8 0 0 0 8 8 0 0 % K
% Leu: 0 0 0 0 0 0 8 0 0 0 8 0 0 22 0 % L
% Met: 0 0 0 0 0 0 8 0 15 43 0 0 0 22 0 % M
% Asn: 0 0 0 15 0 8 50 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 15 0 0 29 0 0 0 0 29 0 15 50 0 % Q
% Arg: 15 43 0 0 0 58 0 8 50 0 0 8 8 0 8 % R
% Ser: 0 8 15 15 36 0 0 50 0 0 0 0 0 0 15 % S
% Thr: 0 22 8 8 22 0 8 0 0 8 0 0 0 0 50 % T
% Val: 0 8 0 0 29 0 0 8 0 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 29 0 8 50 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _