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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WBSCR22 All Species: 26.97
Human Site: S67 Identified Species: 45.64
UniProt: O43709 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43709 NP_059998.2 281 31880 S67 I G C G T G L S G S Y L S D E
Chimpanzee Pan troglodytes XP_001146333 288 32424 S67 I G C G T G L S G S Y L S D E
Rhesus Macaque Macaca mulatta XP_001115175 244 26972 P54 L Y L P E N K P C Y L L D I G
Dog Lupus familis XP_536843 284 32044 S67 I G C G S G L S G D Y L S D E
Cat Felis silvestris
Mouse Mus musculus Q9CY21 281 31568 S67 I G C G S G L S G D Y I S E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034421 282 31481 S67 V G C G S G L S G E H I S E E
Frog Xenopus laevis NP_001085369 282 31627 S67 V G C G S G L S G D Y I S E Q
Zebra Danio Brachydanio rerio NP_001076348 282 31663 S67 V G C G S G L S G D Y L S E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649762 276 31107 S67 C G S G L S G S V L E D S E H
Honey Bee Apis mellifera XP_623810 275 31197 V67 G S G L S G N V I E N Y G H I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786791 283 31707 G67 G C G S G L S G E A L T E Q G
Poplar Tree Populus trichocarpa XP_002300071 289 32108 E67 C G S G L S G E T L T E N G H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200538 289 32368 E67 C G S G L S G E T L S E D G H
Baker's Yeast Sacchar. cerevisiae P25627 275 30724 H71 I L T Q E G D H V W C G L D I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 84.6 82.7 N.A. 79.7 N.A. N.A. N.A. 69.8 66.3 65.9 N.A. 59.7 58.7 N.A. 59.3
Protein Similarity: 100 94.4 84.6 91.9 N.A. 91.4 N.A. N.A. N.A. 83.3 85.1 83.6 N.A. 75 77.5 N.A. 77.3
P-Site Identity: 100 100 6.6 86.6 N.A. 73.3 N.A. N.A. N.A. 60 60 66.6 N.A. 26.6 6.6 N.A. 0
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 N.A. N.A. N.A. 93.3 93.3 86.6 N.A. 33.3 13.3 N.A. 6.6
Percent
Protein Identity: 54.3 N.A. N.A. 52.6 48 N.A.
Protein Similarity: 69.9 N.A. N.A. 68.8 68.3 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 20 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % A
% Cys: 22 8 50 0 0 0 0 0 8 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 29 0 8 15 29 0 % D
% Glu: 0 0 0 0 15 0 0 15 8 15 8 15 8 36 36 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 72 15 72 8 65 22 8 50 0 0 8 8 15 15 % G
% His: 0 0 0 0 0 0 0 8 0 0 8 0 0 8 22 % H
% Ile: 36 0 0 0 0 0 0 0 8 0 0 22 0 8 15 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 8 8 22 8 50 0 0 22 15 36 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 8 0 0 0 8 0 8 0 0 % N
% Pro: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 22 8 43 22 8 58 0 15 8 0 58 0 0 % S
% Thr: 0 0 8 0 15 0 0 0 15 0 8 8 0 0 0 % T
% Val: 22 0 0 0 0 0 0 8 15 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 8 43 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _