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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WBSCR22
All Species:
21.52
Human Site:
T176
Identified Species:
36.41
UniProt:
O43709
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43709
NP_059998.2
281
31880
T176
E
Q
L
E
L
I
T
T
Q
A
T
K
A
G
F
Chimpanzee
Pan troglodytes
XP_001146333
288
32424
T183
P
Q
L
E
L
I
T
T
Q
A
T
K
A
G
F
Rhesus Macaque
Macaca mulatta
XP_001115175
244
26972
A147
K
R
L
Y
C
F
F
A
S
L
F
S
V
L
V
Dog
Lupus familis
XP_536843
284
32044
I176
E
Q
L
E
L
I
T
I
Q
A
T
K
A
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY21
281
31568
T176
E
Q
L
E
L
I
T
T
Q
A
T
R
A
G
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034421
282
31481
A176
E
Q
L
E
L
I
T
A
Q
A
M
R
A
G
F
Frog
Xenopus laevis
NP_001085369
282
31627
A176
Q
Q
L
E
L
V
T
A
Q
A
M
R
A
G
F
Zebra Danio
Brachydanio rerio
NP_001076348
282
31663
A176
E
Q
L
E
L
I
T
A
Q
A
M
K
A
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649762
276
31107
S174
D
Q
I
E
M
V
T
S
Q
A
M
K
A
G
F
Honey Bee
Apis mellifera
XP_623810
275
31197
T173
E
Q
I
E
L
I
T
T
Q
A
T
K
A
G
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786791
283
31707
S175
S
Q
L
E
L
I
T
S
Q
A
M
R
A
G
F
Poplar Tree
Populus trichocarpa
XP_002300071
289
32108
R174
A
Q
R
E
L
I
L
R
S
A
M
H
A
G
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200538
289
32368
R174
A
Q
R
E
L
I
L
R
Q
A
L
Q
A
G
F
Baker's Yeast
Sacchar. cerevisiae
P25627
275
30724
Q171
D
Q
V
D
D
I
L
Q
S
A
K
V
A
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
84.6
82.7
N.A.
79.7
N.A.
N.A.
N.A.
69.8
66.3
65.9
N.A.
59.7
58.7
N.A.
59.3
Protein Similarity:
100
94.4
84.6
91.9
N.A.
91.4
N.A.
N.A.
N.A.
83.3
85.1
83.6
N.A.
75
77.5
N.A.
77.3
P-Site Identity:
100
93.3
6.6
93.3
N.A.
93.3
N.A.
N.A.
N.A.
80
66.6
86.6
N.A.
60
93.3
N.A.
73.3
P-Site Similarity:
100
93.3
20
93.3
N.A.
100
N.A.
N.A.
N.A.
86.6
86.6
86.6
N.A.
93.3
100
N.A.
86.6
Percent
Protein Identity:
54.3
N.A.
N.A.
52.6
48
N.A.
Protein Similarity:
69.9
N.A.
N.A.
68.8
68.3
N.A.
P-Site Identity:
53.3
N.A.
N.A.
60
40
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
29
0
93
0
0
93
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
43
0
0
86
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
8
0
0
0
93
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
15
0
0
79
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
8
43
0
0
0
% K
% Leu:
0
0
65
0
79
0
22
0
0
8
8
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
43
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
93
0
0
0
0
0
8
79
0
0
8
0
0
0
% Q
% Arg:
0
8
15
0
0
0
0
15
0
0
0
29
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
15
22
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
72
29
0
0
36
0
0
0
0
% T
% Val:
0
0
8
0
0
15
0
0
0
0
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _