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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WBSCR22 All Species: 14.85
Human Site: T21 Identified Species: 25.13
UniProt: O43709 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43709 NP_059998.2 281 31880 T21 P E L F Y D E T E A R K Y V R
Chimpanzee Pan troglodytes XP_001146333 288 32424 T21 P E L F Y D E T E A R K Y V R
Rhesus Macaque Macaca mulatta XP_001115175 244 26972 P8 M A S R G R R P E H G G P P E
Dog Lupus familis XP_536843 284 32044 N21 P E L F Y D K N E A R K Y V R
Cat Felis silvestris
Mouse Mus musculus Q9CY21 281 31568 N21 P E L F Y D Q N E A R K Y V R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034421 282 31481 T21 P E L F Y D E T E A R K Y T Q
Frog Xenopus laevis NP_001085369 282 31627 T21 P E L F Y N E T E A R K Y T Q
Zebra Danio Brachydanio rerio NP_001076348 282 31663 E21 P E V F Y N E E E A K K Y S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649762 276 31107 K21 F Y N D D E A K K Y S T N T R
Honey Bee Apis mellifera XP_623810 275 31197 R21 F Y N E S E A R K Y T Q N S R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786791 283 31707 E21 E I F Y N D D E A R K Y T S N
Poplar Tree Populus trichocarpa XP_002300071 289 32108 R21 F Y D D S E A R K Y T S S S R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200538 289 32368 R21 F Y D D T E A R K Y T S S S R
Baker's Yeast Sacchar. cerevisiae P25627 275 30724 S25 E A H K Y T G S T R V Q H I Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 84.6 82.7 N.A. 79.7 N.A. N.A. N.A. 69.8 66.3 65.9 N.A. 59.7 58.7 N.A. 59.3
Protein Similarity: 100 94.4 84.6 91.9 N.A. 91.4 N.A. N.A. N.A. 83.3 85.1 83.6 N.A. 75 77.5 N.A. 77.3
P-Site Identity: 100 100 6.6 86.6 N.A. 86.6 N.A. N.A. N.A. 86.6 80 60 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 6.6 93.3 N.A. 93.3 N.A. N.A. N.A. 93.3 93.3 86.6 N.A. 20 26.6 N.A. 26.6
Percent
Protein Identity: 54.3 N.A. N.A. 52.6 48 N.A.
Protein Similarity: 69.9 N.A. N.A. 68.8 68.3 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 20 N.A. N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 0 0 29 0 8 50 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 22 8 43 8 0 0 0 0 0 0 0 0 % D
% Glu: 15 50 0 8 0 29 36 15 58 0 0 0 0 0 8 % E
% Phe: 29 0 8 50 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 8 0 0 0 8 8 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 8 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 8 0 0 8 8 29 0 15 50 0 0 0 % K
% Leu: 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 15 0 8 15 0 15 0 0 0 0 15 0 8 % N
% Pro: 50 0 0 0 0 0 0 8 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 15 0 0 29 % Q
% Arg: 0 0 0 8 0 8 8 22 0 15 43 0 0 0 58 % R
% Ser: 0 0 8 0 15 0 0 8 0 0 8 15 15 36 0 % S
% Thr: 0 0 0 0 8 8 0 29 8 0 22 8 8 22 0 % T
% Val: 0 0 8 0 0 0 0 0 0 0 8 0 0 29 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 29 0 8 58 0 0 0 0 29 0 8 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _