KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WBSCR22
All Species:
27.88
Human Site:
Y18
Identified Species:
47.18
UniProt:
O43709
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43709
NP_059998.2
281
31880
Y18
G
G
P
P
E
L
F
Y
D
E
T
E
A
R
K
Chimpanzee
Pan troglodytes
XP_001146333
288
32424
Y18
G
G
P
P
E
L
F
Y
D
E
T
E
A
R
K
Rhesus Macaque
Macaca mulatta
XP_001115175
244
26972
Dog
Lupus familis
XP_536843
284
32044
Y18
G
G
P
P
E
L
F
Y
D
K
N
E
A
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY21
281
31568
Y18
S
G
P
P
E
L
F
Y
D
Q
N
E
A
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001034421
282
31481
Y18
R
G
P
P
E
L
F
Y
D
E
T
E
A
R
K
Frog
Xenopus laevis
NP_001085369
282
31627
Y18
T
G
P
P
E
L
F
Y
N
E
T
E
A
R
K
Zebra Danio
Brachydanio rerio
NP_001076348
282
31663
Y18
M
A
P
P
E
V
F
Y
N
E
E
E
A
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649762
276
31107
D18
P
E
I
F
Y
N
D
D
E
A
K
K
Y
S
T
Honey Bee
Apis mellifera
XP_623810
275
31197
S18
P
E
L
F
Y
N
E
S
E
A
R
K
Y
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786791
283
31707
N18
A
P
P
E
I
F
Y
N
D
D
E
A
R
K
Y
Poplar Tree
Populus trichocarpa
XP_002300071
289
32108
S18
P
E
I
F
Y
D
D
S
E
A
R
K
Y
T
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200538
289
32368
T18
P
E
I
F
Y
D
D
T
E
A
R
K
Y
T
S
Baker's Yeast
Sacchar. cerevisiae
P25627
275
30724
Y22
N
D
S
E
A
H
K
Y
T
G
S
T
R
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
84.6
82.7
N.A.
79.7
N.A.
N.A.
N.A.
69.8
66.3
65.9
N.A.
59.7
58.7
N.A.
59.3
Protein Similarity:
100
94.4
84.6
91.9
N.A.
91.4
N.A.
N.A.
N.A.
83.3
85.1
83.6
N.A.
75
77.5
N.A.
77.3
P-Site Identity:
100
100
0
86.6
N.A.
80
N.A.
N.A.
N.A.
93.3
86.6
60
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
0
93.3
N.A.
86.6
N.A.
N.A.
N.A.
93.3
93.3
80
N.A.
13.3
20
N.A.
33.3
Percent
Protein Identity:
54.3
N.A.
N.A.
52.6
48
N.A.
Protein Similarity:
69.9
N.A.
N.A.
68.8
68.3
N.A.
P-Site Identity:
0
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
0
29
0
8
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
15
22
8
43
8
0
0
0
0
0
% D
% Glu:
0
29
0
15
50
0
8
0
29
36
15
50
0
0
0
% E
% Phe:
0
0
0
29
0
8
50
0
0
0
0
0
0
0
0
% F
% Gly:
22
43
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
22
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
8
29
0
15
50
% K
% Leu:
0
0
8
0
0
43
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
15
0
8
15
0
15
0
0
0
0
% N
% Pro:
29
8
58
50
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
15
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
22
0
15
43
0
% R
% Ser:
8
0
8
0
0
0
0
15
0
0
8
0
0
8
15
% S
% Thr:
8
0
0
0
0
0
0
8
8
0
29
8
0
22
8
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
29
0
8
58
0
0
0
0
29
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _