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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX3
All Species:
22.12
Human Site:
S251
Identified Species:
44.24
UniProt:
O43711
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43711
NP_066305.2
291
31867
S251
Q
H
D
A
F
Q
K
S
L
N
D
S
I
Q
P
Chimpanzee
Pan troglodytes
XP_001169592
330
34351
S286
Q
Q
E
A
F
Q
K
S
L
A
Q
P
L
P
A
Rhesus Macaque
Macaca mulatta
XP_001109904
336
34781
S292
Q
Q
E
A
F
Q
K
S
L
A
Q
P
L
P
A
Dog
Lupus familis
XP_546241
637
68285
S597
Q
H
D
A
F
Q
K
S
L
N
D
S
I
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
O55144
291
31705
S251
Q
H
D
A
F
Q
K
S
L
N
D
S
I
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
S295
H
Q
E
A
F
Q
K
S
L
A
Q
P
L
L
D
Chicken
Gallus gallus
O93367
297
32351
S257
Q
H
D
A
F
Q
K
S
L
N
E
S
I
Q
P
Frog
Xenopus laevis
Q8JJ64
306
34004
E263
R
V
P
I
L
Y
H
E
N
S
S
S
A
E
S
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
E255
R
V
P
I
L
Y
H
E
N
S
A
S
E
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
Y553
L
V
R
V
P
V
L
Y
H
D
G
T
T
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
D108
S
E
L
A
K
R
L
D
V
T
E
T
Q
V
K
Sea Urchin
Strong. purpuratus
Q26656
405
44721
A338
A
N
L
A
Q
V
S
A
V
H
V
H
A
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.5
51.4
45.5
N.A.
98.9
N.A.
N.A.
46.7
80.8
23.8
24.9
N.A.
20.4
N.A.
25.7
27.4
Protein Similarity:
100
59.3
59.2
45.5
N.A.
99.3
N.A.
N.A.
56.6
85.8
38.5
40.7
N.A.
28
N.A.
37.1
40.4
P-Site Identity:
100
46.6
46.6
100
N.A.
100
N.A.
N.A.
40
93.3
6.6
6.6
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
60
60
100
N.A.
100
N.A.
N.A.
53.3
100
26.6
20
N.A.
13.3
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
75
0
0
0
9
0
25
9
0
17
9
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
0
0
9
0
9
25
0
0
0
9
% D
% Glu:
0
9
25
0
0
0
0
17
0
0
17
0
9
9
0
% E
% Phe:
0
0
0
0
59
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% G
% His:
9
34
0
0
0
0
17
0
9
9
0
9
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
0
0
0
0
0
34
0
0
% I
% Lys:
0
0
0
0
9
0
59
0
0
0
0
0
0
0
9
% K
% Leu:
9
0
17
0
17
0
17
0
59
0
0
0
25
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
17
34
0
0
0
0
0
% N
% Pro:
0
0
17
0
9
0
0
0
0
0
0
25
0
17
34
% P
% Gln:
50
25
0
0
9
59
0
0
0
0
25
0
9
34
0
% Q
% Arg:
17
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
9
59
0
17
9
50
0
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
17
9
0
9
% T
% Val:
0
25
0
9
0
17
0
0
17
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
9
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _