KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX3
All Species:
23.64
Human Site:
S266
Identified Species:
47.27
UniProt:
O43711
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43711
NP_066305.2
291
31867
S266
D
P
L
C
L
H
N
S
S
L
F
A
L
Q
N
Chimpanzee
Pan troglodytes
XP_001169592
330
34351
S301
D
P
L
C
V
H
N
S
S
L
F
A
L
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001109904
336
34781
S307
D
P
L
C
V
H
N
S
S
L
F
A
L
Q
N
Dog
Lupus familis
XP_546241
637
68285
S612
D
P
L
C
L
H
N
S
S
L
F
A
L
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
O55144
291
31705
S266
D
P
L
C
L
H
N
S
S
L
F
A
L
Q
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
L310
Q
P
L
Q
A
D
P
L
C
V
H
N
S
S
L
Chicken
Gallus gallus
O93367
297
32351
S272
D
P
L
C
L
H
N
S
S
L
F
A
L
Q
N
Frog
Xenopus laevis
Q8JJ64
306
34004
P278
A
S
S
A
A
N
V
P
V
S
Q
P
L
L
T
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
V270
N
T
A
G
N
V
P
V
S
Q
P
L
L
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
H568
F
V
P
P
P
P
P
H
H
H
P
M
Q
Y
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
T123
I
W
F
Q
N
R
R
T
K
W
K
K
I
E
S
Sea Urchin
Strong. purpuratus
Q26656
405
44721
I353
Q
R
M
V
R
V
P
I
L
Y
H
E
N
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.5
51.4
45.5
N.A.
98.9
N.A.
N.A.
46.7
80.8
23.8
24.9
N.A.
20.4
N.A.
25.7
27.4
Protein Similarity:
100
59.3
59.2
45.5
N.A.
99.3
N.A.
N.A.
56.6
85.8
38.5
40.7
N.A.
28
N.A.
37.1
40.4
P-Site Identity:
100
86.6
93.3
100
N.A.
100
N.A.
N.A.
13.3
100
6.6
13.3
N.A.
0
N.A.
0
0
P-Site Similarity:
100
93.3
100
100
N.A.
100
N.A.
N.A.
20
100
13.3
20
N.A.
0
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
17
0
0
0
0
0
0
50
0
0
0
% A
% Cys:
0
0
0
50
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% E
% Phe:
9
0
9
0
0
0
0
0
0
0
50
0
0
0
9
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
50
0
9
9
9
17
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% K
% Leu:
0
0
59
0
34
0
0
9
9
50
0
9
67
9
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
0
0
0
17
9
50
0
0
0
0
9
9
0
42
% N
% Pro:
0
59
9
9
9
9
34
9
0
0
17
9
0
0
9
% P
% Gln:
17
0
0
17
0
0
0
0
0
9
9
0
9
50
0
% Q
% Arg:
0
9
0
0
9
9
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
0
0
0
0
50
59
9
0
0
9
9
9
% S
% Thr:
0
9
0
0
0
0
0
9
0
0
0
0
0
9
9
% T
% Val:
0
9
0
9
17
17
9
9
9
9
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _