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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX3
All Species:
16.97
Human Site:
S282
Identified Species:
33.94
UniProt:
O43711
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43711
NP_066305.2
291
31867
S282
Q
P
W
E
E
D
S
S
K
V
P
A
V
T
S
Chimpanzee
Pan troglodytes
XP_001169592
330
34351
T317
Q
P
W
S
D
D
S
T
K
I
T
S
V
T
S
Rhesus Macaque
Macaca mulatta
XP_001109904
336
34781
T323
Q
P
W
S
D
D
S
T
K
I
T
S
V
T
S
Dog
Lupus familis
XP_546241
637
68285
S628
Q
P
W
E
E
D
S
S
K
V
P
A
V
T
S
Cat
Felis silvestris
Mouse
Mus musculus
O55144
291
31705
S282
Q
P
W
E
E
D
S
S
K
V
P
A
V
T
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
W326
A
L
Q
N
L
Q
P
W
S
D
D
T
A
K
I
Chicken
Gallus gallus
O93367
297
32351
A288
Q
P
W
E
E
E
S
A
K
I
P
P
V
T
S
Frog
Xenopus laevis
Q8JJ64
306
34004
H294
P
H
P
V
Y
Y
S
H
P
V
V
T
S
V
P
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
P286
H
P
V
Y
Y
S
H
P
I
V
T
S
V
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
P584
A
A
R
N
T
S
P
P
R
P
P
L
S
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
P139
K
E
R
S
G
E
I
P
D
D
Q
I
V
K
P
Sea Urchin
Strong. purpuratus
Q26656
405
44721
P369
T
G
S
S
L
H
S
P
N
I
L
P
F
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.5
51.4
45.5
N.A.
98.9
N.A.
N.A.
46.7
80.8
23.8
24.9
N.A.
20.4
N.A.
25.7
27.4
Protein Similarity:
100
59.3
59.2
45.5
N.A.
99.3
N.A.
N.A.
56.6
85.8
38.5
40.7
N.A.
28
N.A.
37.1
40.4
P-Site Identity:
100
60
60
100
N.A.
100
N.A.
N.A.
0
73.3
13.3
20
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
N.A.
N.A.
0
93.3
13.3
26.6
N.A.
20
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
0
0
0
9
0
0
0
25
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
42
0
0
9
17
9
0
0
0
0
% D
% Glu:
0
9
0
34
34
17
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
9
0
0
0
9
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
34
0
9
0
0
9
% I
% Lys:
9
0
0
0
0
0
0
0
50
0
0
0
0
17
0
% K
% Leu:
0
9
0
0
17
0
0
0
0
0
9
9
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
17
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
9
59
9
0
0
0
17
34
9
9
42
17
0
17
17
% P
% Gln:
50
0
9
0
0
9
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
9
34
0
17
67
25
9
0
0
25
17
9
50
% S
% Thr:
9
0
0
0
9
0
0
17
0
0
25
17
0
50
0
% T
% Val:
0
0
9
9
0
0
0
0
0
42
9
0
67
9
0
% V
% Trp:
0
0
50
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
17
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _