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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX3
All Species:
9.7
Human Site:
S58
Identified Species:
19.39
UniProt:
O43711
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43711
NP_066305.2
291
31867
S58
R
P
G
A
T
Y
P
S
L
P
A
S
F
A
G
Chimpanzee
Pan troglodytes
XP_001169592
330
34351
G59
G
G
A
Y
T
Y
G
G
G
G
S
A
A
G
A
Rhesus Macaque
Macaca mulatta
XP_001109904
336
34781
G89
P
G
G
P
G
G
P
G
G
P
A
G
G
G
G
Dog
Lupus familis
XP_546241
637
68285
S404
R
P
G
A
T
Y
P
S
L
P
A
S
F
A
G
Cat
Felis silvestris
Mouse
Mus musculus
O55144
291
31705
S58
R
P
G
A
A
Y
P
S
L
P
A
S
F
A
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
T59
S
G
A
Y
N
T
M
T
G
G
Y
S
A
S
A
Chicken
Gallus gallus
O93367
297
32351
F58
R
G
P
D
G
A
A
F
L
G
G
P
R
G
G
Frog
Xenopus laevis
Q8JJ64
306
34004
I66
F
T
F
P
R
L
E
I
P
T
Q
R
F
A
L
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
E61
E
I
N
F
P
R
F
E
L
P
T
Q
R
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
Q270
Q
P
G
A
G
G
P
Q
D
A
A
M
L
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Sea Urchin
Strong. purpuratus
Q26656
405
44721
P119
I
Y
G
S
T
R
H
P
L
S
A
T
V
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.5
51.4
45.5
N.A.
98.9
N.A.
N.A.
46.7
80.8
23.8
24.9
N.A.
20.4
N.A.
25.7
27.4
Protein Similarity:
100
59.3
59.2
45.5
N.A.
99.3
N.A.
N.A.
56.6
85.8
38.5
40.7
N.A.
28
N.A.
37.1
40.4
P-Site Identity:
100
13.3
33.3
100
N.A.
93.3
N.A.
N.A.
6.6
20
13.3
13.3
N.A.
33.3
N.A.
0
33.3
P-Site Similarity:
100
26.6
33.3
100
N.A.
93.3
N.A.
N.A.
20
20
13.3
13.3
N.A.
46.6
N.A.
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
34
9
9
9
0
0
9
50
9
17
34
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% E
% Phe:
9
0
9
9
0
0
9
9
0
0
0
0
34
9
0
% F
% Gly:
9
34
50
0
25
17
9
17
25
25
9
9
9
25
50
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
50
0
0
0
9
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
34
9
17
9
0
42
9
9
42
0
9
0
9
0
% P
% Gln:
9
0
0
0
0
0
0
9
0
0
9
9
0
0
0
% Q
% Arg:
34
0
0
0
9
17
0
0
0
0
0
9
17
0
9
% R
% Ser:
9
0
0
9
0
0
0
25
0
9
9
34
0
17
0
% S
% Thr:
0
9
0
0
34
9
0
9
0
9
9
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
17
0
34
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _