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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX3
All Species:
27.27
Human Site:
T162
Identified Species:
54.55
UniProt:
O43711
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43711
NP_066305.2
291
31867
T162
G
H
P
Y
Q
N
R
T
P
P
K
R
K
K
P
Chimpanzee
Pan troglodytes
XP_001169592
330
34351
T197
G
H
P
Y
Q
N
R
T
P
P
K
K
K
K
P
Rhesus Macaque
Macaca mulatta
XP_001109904
336
34781
T203
G
H
P
Y
Q
N
R
T
P
P
K
K
K
K
P
Dog
Lupus familis
XP_546241
637
68285
T508
G
H
P
Y
Q
N
R
T
P
P
K
R
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
O55144
291
31705
T162
G
H
P
Y
Q
N
R
T
P
P
K
R
K
K
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
T206
G
H
P
Y
Q
N
R
T
P
P
K
K
K
K
P
Chicken
Gallus gallus
O93367
297
32351
T168
G
H
P
Y
Q
N
R
T
P
P
K
R
K
K
P
Frog
Xenopus laevis
Q8JJ64
306
34004
K174
R
E
D
S
P
D
K
K
P
C
R
K
K
K
T
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
K166
S
D
D
G
A
D
K
K
P
C
R
K
K
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
L364
L
H
P
L
Y
H
P
L
G
S
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
D20
Y
F
A
L
L
T
S
D
V
K
P
Q
R
R
T
Sea Urchin
Strong. purpuratus
Q26656
405
44721
P249
D
D
D
D
D
Q
S
P
Q
K
K
K
K
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.5
51.4
45.5
N.A.
98.9
N.A.
N.A.
46.7
80.8
23.8
24.9
N.A.
20.4
N.A.
25.7
27.4
Protein Similarity:
100
59.3
59.2
45.5
N.A.
99.3
N.A.
N.A.
56.6
85.8
38.5
40.7
N.A.
28
N.A.
37.1
40.4
P-Site Identity:
100
93.3
93.3
100
N.A.
100
N.A.
N.A.
93.3
100
20
20
N.A.
13.3
N.A.
0
20
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
46.6
46.6
N.A.
46.6
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% C
% Asp:
9
17
25
9
9
17
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
59
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
67
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
17
0
17
67
50
84
84
0
% K
% Leu:
9
0
0
17
9
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
67
0
9
0
9
9
75
59
9
0
0
0
59
% P
% Gln:
0
0
0
0
59
9
0
0
9
0
9
17
9
9
9
% Q
% Arg:
9
0
0
0
0
0
59
0
0
0
17
34
9
9
0
% R
% Ser:
9
0
0
9
0
0
17
0
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
59
0
0
0
0
0
0
34
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
59
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _