KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HTATSF1
All Species:
9.09
Human Site:
S258
Identified Species:
20
UniProt:
O43719
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43719
NP_001156752.1
755
85853
S258
P
E
R
R
A
G
P
S
R
M
R
H
E
R
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082693
754
85584
S258
P
E
R
R
A
G
P
S
R
M
R
H
E
R
V
Dog
Lupus familis
XP_538183
914
103721
S404
P
E
R
R
A
G
P
S
R
M
R
H
E
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGC0
757
86221
N259
P
E
R
R
A
G
P
N
R
L
R
H
E
R
V
Rat
Rattus norvegicus
NP_001101729
776
88606
N258
P
E
R
R
A
G
P
N
R
L
R
H
E
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514214
429
48692
Chicken
Gallus gallus
XP_001233032
450
51060
A22
Q
L
Q
Q
Q
Y
E
A
D
R
G
G
E
G
D
Frog
Xenopus laevis
NP_001083090
452
51903
R24
L
Q
E
L
Y
G
E
R
E
A
G
D
G
Q
D
Zebra Danio
Brachydanio rerio
NP_957497
450
51239
E22
L
R
L
Q
Q
L
Y
E
Q
R
Q
E
N
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391935
353
41235
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793195
462
53264
G34
I
Y
T
D
P
N
D
G
T
M
Y
E
W
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
69.2
N.A.
76.2
75.3
N.A.
41.3
41.7
39.4
37.8
N.A.
N.A.
21
N.A.
22.2
Protein Similarity:
100
N.A.
97.8
74.4
N.A.
86.6
85.5
N.A.
49.4
49.9
48.8
48.2
N.A.
N.A.
31.5
N.A.
37.2
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
0
6.6
6.6
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
26.6
20
20
N.A.
N.A.
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
46
0
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
10
0
0
10
0
10
28
% D
% Glu:
0
46
10
0
0
0
19
10
10
0
0
19
55
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
55
0
10
0
0
19
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
46
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
10
10
10
0
10
0
0
0
19
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
37
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
19
0
0
0
0
10
0
0
% N
% Pro:
46
0
0
0
10
0
46
0
0
0
0
0
0
0
10
% P
% Gln:
10
10
10
19
19
0
0
0
10
0
10
0
0
10
0
% Q
% Arg:
0
10
46
46
0
0
0
10
46
19
46
0
0
46
0
% R
% Ser:
0
0
0
0
0
0
0
28
0
0
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
10
0
0
10
10
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _