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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITM2A
All Species:
8.48
Human Site:
S134
Identified Species:
20.74
UniProt:
O43736
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43736
NP_004858.1
263
29741
S134
D
V
P
V
P
S
F
S
D
S
D
P
A
A
I
Chimpanzee
Pan troglodytes
XP_001145755
179
20536
L73
T
A
Y
L
D
L
L
L
G
N
C
Y
L
M
P
Rhesus Macaque
Macaca mulatta
XP_001102261
226
25686
D120
E
E
A
D
I
R
E
D
D
N
I
A
I
I
D
Dog
Lupus familis
XP_534119
258
29889
A130
S
V
P
V
P
E
F
A
D
S
D
P
A
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61500
263
29673
S134
D
V
P
V
P
S
F
S
D
S
D
P
A
A
I
Rat
Rattus norvegicus
Q5XIE8
266
30295
A138
S
V
P
V
P
E
F
A
D
S
D
P
A
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514703
228
25777
L122
T
A
Y
L
D
L
Q
L
G
N
C
Y
V
I
P
Chicken
Gallus gallus
O42204
262
29991
A133
S
V
P
V
P
E
F
A
D
S
D
P
A
D
I
Frog
Xenopus laevis
NP_001079561
247
28022
D131
A
A
I
L
H
D
F
D
R
L
L
T
A
Y
L
Zebra Danio
Brachydanio rerio
NP_955940
261
30494
S132
N
I
P
V
P
K
F
S
D
S
D
P
A
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68
85.9
40.2
N.A.
95
40.2
N.A.
58.9
38.7
58.1
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
68
85.9
59.7
N.A.
96.5
60.9
N.A.
74.1
60.8
74.9
61.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
73.3
N.A.
100
73.3
N.A.
0
73.3
13.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
80
N.A.
100
80
N.A.
13.3
80
26.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
30
10
0
0
0
0
30
0
0
0
10
70
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% C
% Asp:
20
0
0
10
20
10
0
20
70
0
60
0
0
20
10
% D
% Glu:
10
10
0
0
0
30
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
10
0
0
0
0
0
10
0
10
20
60
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
30
0
20
10
20
0
10
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
30
0
0
0
20
0
% N
% Pro:
0
0
60
0
60
0
0
0
0
0
0
60
0
0
20
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% R
% Ser:
30
0
0
0
0
20
0
30
0
60
0
0
0
0
0
% S
% Thr:
20
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
50
0
60
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
0
0
20
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _