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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB2
All Species:
14.55
Human Site:
S21
Identified Species:
24.62
UniProt:
O43741
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43741
NP_005390.1
272
30302
S21
H
G
A
K
A
A
R
S
E
G
A
G
G
H
A
Chimpanzee
Pan troglodytes
XP_513749
272
30341
S21
H
G
A
K
A
A
R
S
E
G
A
G
G
H
A
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
S21
H
G
A
K
A
A
R
S
E
G
A
G
G
H
A
Dog
Lupus familis
XP_850153
272
30208
A21
T
A
P
K
S
S
R
A
E
G
A
G
G
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAM0
271
30191
A21
H
G
A
K
A
A
R
A
E
G
G
G
H
G
P
Rat
Rattus norvegicus
Q9QZH4
271
30209
A21
H
G
A
K
A
A
R
A
E
G
G
G
H
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
G26
L
G
E
E
G
L
A
G
S
G
G
R
I
R
T
Chicken
Gallus gallus
NP_001038127
274
30623
S21
H
G
S
K
S
H
R
S
D
G
S
G
T
A
H
Frog
Xenopus laevis
NP_001080680
271
30218
D21
H
G
K
S
H
R
A
D
G
A
T
A
G
H
S
Zebra Danio
Brachydanio rerio
NP_001124105
269
29655
G21
P
Q
R
S
D
S
G
G
Q
R
D
L
E
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393160
283
31818
E21
H
T
S
N
T
N
R
E
H
R
H
V
K
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
E21
S
S
L
S
P
T
K
E
S
M
S
S
S
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
S32
I
C
S
R
E
A
M
S
A
A
S
D
G
N
H
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
N54
K
V
T
E
L
S
L
N
K
C
S
D
S
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.7
N.A.
97
97
N.A.
75
89.7
84.5
75
N.A.
N.A.
51.5
N.A.
51.2
Protein Similarity:
100
99.6
99.6
95.2
N.A.
98.1
98.1
N.A.
82.1
94.8
91.5
84.1
N.A.
N.A.
65.7
N.A.
63.8
P-Site Identity:
100
100
100
60
N.A.
66.6
66.6
N.A.
13.3
46.6
26.6
0
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
73.3
73.3
N.A.
20
73.3
33.3
20
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
36
0
36
43
15
22
8
15
29
8
0
8
29
% A
% Cys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
8
0
8
15
0
0
15
% D
% Glu:
0
0
8
15
8
0
0
15
43
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
58
0
0
8
0
8
15
8
58
22
50
43
15
0
% G
% His:
58
0
0
0
8
8
0
0
8
0
8
0
15
36
15
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
8
50
0
0
8
0
8
0
0
0
8
0
0
% K
% Leu:
8
0
8
0
8
8
8
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
8
0
0
0
0
0
8
0
% N
% Pro:
8
0
8
0
8
0
0
0
0
0
0
0
0
8
15
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
0
8
8
0
8
58
0
0
15
0
8
0
8
0
% R
% Ser:
8
8
22
22
15
22
0
36
15
0
29
8
15
0
15
% S
% Thr:
8
8
8
0
8
8
0
0
0
0
8
0
8
0
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _