KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB2
All Species:
30.61
Human Site:
S47
Identified Species:
51.79
UniProt:
O43741
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43741
NP_005390.1
272
30302
S47
T
D
D
P
S
V
F
S
L
P
D
S
K
L
P
Chimpanzee
Pan troglodytes
XP_513749
272
30341
S47
T
D
D
P
N
V
F
S
L
P
D
S
K
L
P
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
S47
T
D
D
P
S
V
F
S
L
P
D
S
K
L
P
Dog
Lupus familis
XP_850153
272
30208
S47
T
D
D
P
S
V
F
S
L
P
D
P
K
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAM0
271
30191
S46
T
D
D
P
S
V
F
S
L
P
D
S
K
L
P
Rat
Rattus norvegicus
Q9QZH4
271
30209
S46
T
D
D
P
S
V
F
S
L
P
D
S
K
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
S60
V
I
Q
S
P
L
R
S
L
F
Q
T
Q
L
P
Chicken
Gallus gallus
NP_001038127
274
30623
S49
T
D
D
P
S
V
F
S
S
H
D
S
K
I
P
Frog
Xenopus laevis
NP_001080680
271
30218
N46
V
G
S
T
D
D
P
N
I
F
S
T
Q
E
S
Zebra Danio
Brachydanio rerio
NP_001124105
269
29655
P45
N
I
F
N
T
H
G
P
E
S
K
A
A
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393160
283
31818
S54
S
Q
K
L
V
F
Q
S
S
H
E
E
E
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
R52
S
I
D
L
P
A
G
R
F
R
E
L
M
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
S59
H
S
P
R
A
T
Q
S
P
L
M
F
A
P
Q
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
G134
S
P
D
D
D
R
S
G
H
S
S
P
R
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.7
N.A.
97
97
N.A.
75
89.7
84.5
75
N.A.
N.A.
51.5
N.A.
51.2
Protein Similarity:
100
99.6
99.6
95.2
N.A.
98.1
98.1
N.A.
82.1
94.8
91.5
84.1
N.A.
N.A.
65.7
N.A.
63.8
P-Site Identity:
100
93.3
100
93.3
N.A.
100
100
N.A.
26.6
80
0
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
46.6
86.6
26.6
13.3
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
8
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
65
8
15
8
0
0
0
0
50
0
0
0
15
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
15
8
8
22
8
% E
% Phe:
0
0
8
0
0
8
50
0
8
15
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
0
15
8
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
8
0
0
8
15
0
0
0
0
0
% H
% Ile:
0
22
0
0
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
8
0
50
0
0
% K
% Leu:
0
0
0
15
0
8
0
0
50
8
0
8
0
50
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
8
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
50
15
0
8
8
8
43
0
15
0
8
65
% P
% Gln:
0
8
8
0
0
0
15
0
0
0
8
0
15
0
8
% Q
% Arg:
0
0
0
8
0
8
8
8
0
8
0
0
8
8
0
% R
% Ser:
22
8
8
8
43
0
8
72
15
15
15
43
0
0
8
% S
% Thr:
50
0
0
8
8
8
0
0
0
0
0
15
0
0
0
% T
% Val:
15
0
0
0
8
50
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _