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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1G1
All Species:
18.79
Human Site:
S549
Identified Species:
34.44
UniProt:
O43747
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43747
NP_001025178.1
822
91351
S549
N
R
I
K
K
V
V
S
I
Y
G
S
S
I
D
Chimpanzee
Pan troglodytes
XP_001171290
801
88711
R526
N
M
S
T
S
V
T
R
G
Y
A
L
T
A
I
Rhesus Macaque
Macaca mulatta
XP_001109007
785
86931
K512
E
V
L
A
L
L
E
K
V
L
Q
S
H
M
S
Dog
Lupus familis
XP_862506
822
91393
S549
N
R
I
K
K
V
V
S
I
Y
G
S
S
I
D
Cat
Felis silvestris
Mouse
Mus musculus
P22892
822
91332
S549
N
R
I
K
K
V
V
S
I
Y
G
S
S
I
D
Rat
Rattus norvegicus
P18484
938
104026
D572
D
S
Q
L
K
N
A
D
V
E
L
Q
Q
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509435
822
91369
S549
N
R
I
K
K
V
V
S
I
Y
G
S
S
I
D
Chicken
Gallus gallus
NP_001006132
821
91444
S552
N
R
I
K
K
V
V
S
I
Y
G
S
S
I
D
Frog
Xenopus laevis
NP_001083997
812
90423
S539
K
N
S
T
R
F
N
S
T
V
N
R
I
K
K
Zebra Danio
Brachydanio rerio
NP_955976
819
90933
I549
R
I
K
K
V
V
S
I
Y
G
S
S
I
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
D573
H
S
N
L
R
S
A
D
A
E
L
Q
Q
R
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792773
959
106235
K660
E
R
I
E
K
I
V
K
P
Y
T
R
S
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12028
832
93606
N561
Q
E
L
Y
T
A
T
N
L
K
I
I
N
Y
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
60.5
99.5
N.A.
99.2
23.6
N.A.
98.6
96.8
90.5
90.2
N.A.
22.5
N.A.
N.A.
52.9
Protein Similarity:
100
96.7
76
99.7
N.A.
99.6
47.7
N.A.
99.3
98.3
94.5
95.3
N.A.
45.2
N.A.
N.A.
67.2
P-Site Identity:
100
20
6.6
100
N.A.
100
6.6
N.A.
100
100
6.6
20
N.A.
0
N.A.
N.A.
46.6
P-Site Similarity:
100
26.6
33.3
100
N.A.
100
20
N.A.
100
100
13.3
20
N.A.
13.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
16
0
8
0
8
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
16
0
0
0
0
0
8
47
% D
% Glu:
16
8
0
8
0
0
8
0
0
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
39
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
47
0
0
8
0
8
39
0
8
8
16
39
16
% I
% Lys:
8
0
8
47
54
0
0
16
0
8
0
0
0
8
8
% K
% Leu:
0
0
16
16
8
8
0
0
8
8
16
8
0
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
47
8
8
0
0
8
8
8
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
8
16
16
0
0
% Q
% Arg:
8
47
0
0
16
0
0
8
0
0
0
16
0
16
0
% R
% Ser:
0
16
16
0
8
8
8
47
0
0
8
54
47
0
8
% S
% Thr:
0
0
0
16
8
0
16
0
8
0
8
0
8
0
0
% T
% Val:
0
8
0
0
8
54
47
0
16
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
54
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _