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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP1G1 All Species: 19.7
Human Site: S623 Identified Species: 36.11
UniProt: O43747 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43747 NP_001025178.1 822 91351 S623 P S G P Q P T S Q A N D L L D
Chimpanzee Pan troglodytes XP_001171290 801 88711 E600 V T T N G P T E I V Q T N G E
Rhesus Macaque Macaca mulatta XP_001109007 785 86931 P586 A A I L E K M P L V E R D G P
Dog Lupus familis XP_862506 822 91393 S623 P S G P Q P T S Q A N D L L D
Cat Felis silvestris
Mouse Mus musculus P22892 822 91332 S623 P S G P Q P T S Q A N D L L D
Rat Rattus norvegicus P18484 938 104026 P646 N G G P E P V P A S T S A A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509435 822 91369 S623 P T G P Q P T S Q A N D L L D
Chicken Gallus gallus NP_001006132 821 91444 S626 H S G L Q P G S Q A N D L L D
Frog Xenopus laevis NP_001083997 812 90423 K613 D P T I I D A K P V Q S T P Q
Zebra Danio Brachydanio rerio NP_955976 819 90933 Q623 N I P Q P I S Q A N D L L D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91926 940 105602 L647 S A A Q N N A L V N N S H S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792773 959 106235 S734 A P S H D E G S S L V D L L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12028 832 93606 T635 M P K F E K I T E E Q D N G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 60.5 99.5 N.A. 99.2 23.6 N.A. 98.6 96.8 90.5 90.2 N.A. 22.5 N.A. N.A. 52.9
Protein Similarity: 100 96.7 76 99.7 N.A. 99.6 47.7 N.A. 99.3 98.3 94.5 95.3 N.A. 45.2 N.A. N.A. 67.2
P-Site Identity: 100 13.3 0 100 N.A. 100 20 N.A. 93.3 80 0 6.6 N.A. 6.6 N.A. N.A. 26.6
P-Site Similarity: 100 26.6 13.3 100 N.A. 100 33.3 N.A. 100 80 0 20 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 53 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 16 8 0 0 0 16 0 16 39 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 8 0 0 0 0 8 54 8 8 39 % D
% Glu: 0 0 0 0 24 8 0 8 8 8 8 0 0 0 8 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 47 0 8 0 16 0 0 0 0 0 0 24 8 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 8 8 8 8 8 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 16 0 8 0 0 0 0 0 0 16 % K
% Leu: 0 0 0 16 0 0 0 8 8 8 0 8 54 47 8 % L
% Met: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 8 8 8 0 0 0 16 47 0 16 0 0 % N
% Pro: 31 24 8 39 8 54 0 16 8 0 0 0 0 8 8 % P
% Gln: 0 0 0 16 39 0 0 8 39 0 24 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 8 31 8 0 0 0 8 47 8 8 0 24 0 8 8 % S
% Thr: 0 16 16 0 0 0 39 8 0 0 8 8 8 0 0 % T
% Val: 8 0 0 0 0 0 8 0 8 24 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _