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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP1G1 All Species: 17.58
Human Site: Y710 Identified Species: 32.22
UniProt: O43747 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43747 NP_001025178.1 822 91351 Y710 G I P S I T A Y S K N G L K I
Chimpanzee Pan troglodytes XP_001171290 801 88711 P687 S V P Q I S Q P P F L L D G L
Rhesus Macaque Macaca mulatta XP_001109007 785 86931 F673 P I P D L K V F E R E G V Q L
Dog Lupus familis XP_862506 822 91393 Y710 G I P S I T A Y S K N G L K I
Cat Felis silvestris
Mouse Mus musculus P22892 822 91332 Y710 G I P S I T A Y S K N G L K I
Rat Rattus norvegicus P18484 938 104026 N733 L K S E F R Q N L G R M F I F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509435 822 91369 Y710 G I P S I T A Y S K N G L K I
Chicken Gallus gallus NP_001006132 821 91444 G713 I T A Y N K N G L K I D F S F
Frog Xenopus laevis NP_001083997 812 90423 Y700 G I T P I T A Y N K N G L K I
Zebra Danio Brachydanio rerio NP_955976 819 90933 N710 P M T A Y N K N G L K I E F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91926 940 105602 Q734 G V K S E F R Q N L G R L G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792773 959 106235 P821 P P P G S V P P A L G M N S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12028 832 93606 L722 N S G V T L P L D A N K I Y D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 60.5 99.5 N.A. 99.2 23.6 N.A. 98.6 96.8 90.5 90.2 N.A. 22.5 N.A. N.A. 52.9
Protein Similarity: 100 96.7 76 99.7 N.A. 99.6 47.7 N.A. 99.3 98.3 94.5 95.3 N.A. 45.2 N.A. N.A. 67.2
P-Site Identity: 100 13.3 20 100 N.A. 100 0 N.A. 100 6.6 80 0 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 33.3 60 100 N.A. 100 0 N.A. 100 6.6 86.6 13.3 N.A. 40 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 53 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 39 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 8 0 0 8 8 0 8 % D
% Glu: 0 0 0 8 8 0 0 0 8 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 8 8 0 8 0 8 0 0 16 8 16 % F
% Gly: 47 0 8 8 0 0 0 8 8 8 16 47 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 47 0 0 47 0 0 0 0 0 8 8 8 8 39 % I
% Lys: 0 8 8 0 0 16 8 0 0 47 8 8 0 39 0 % K
% Leu: 8 0 0 0 8 8 0 8 16 24 8 8 47 0 31 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 8 0 0 0 8 8 8 16 16 0 47 0 8 0 0 % N
% Pro: 24 8 54 8 0 0 16 16 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 16 8 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 8 8 0 0 8 8 8 0 0 0 % R
% Ser: 8 8 8 39 8 8 0 0 31 0 0 0 0 16 0 % S
% Thr: 0 8 16 0 8 39 0 0 0 0 0 0 0 0 8 % T
% Val: 0 16 0 8 0 8 8 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 0 39 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _