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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX6
All Species:
28.79
Human Site:
S109
Identified Species:
42.22
UniProt:
O43752
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43752
NP_005810.1
255
29176
S109
M
K
D
Q
M
S
T
S
S
V
Q
A
L
A
E
Chimpanzee
Pan troglodytes
XP_001159596
200
22796
Y86
A
A
A
Y
S
P
S
Y
L
G
D
R
E
L
Q
Rhesus Macaque
Macaca mulatta
XP_001114975
255
29127
S109
M
K
D
Q
M
S
T
S
S
V
Q
A
L
A
E
Dog
Lupus familis
XP_547423
255
29118
S109
M
K
D
Q
M
S
A
S
S
V
Q
A
L
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
S109
M
K
D
Q
M
S
A
S
S
V
Q
A
L
A
E
Rat
Rattus norvegicus
Q63635
255
29038
S109
M
K
D
Q
M
S
A
S
S
V
Q
A
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
S143
M
K
D
Q
M
S
S
S
S
V
Q
A
L
T
E
Chicken
Gallus gallus
Q5ZL19
254
29137
S109
M
K
D
Q
M
S
N
S
S
M
Q
A
L
A
E
Frog
Xenopus laevis
NP_001085148
254
29254
P109
M
K
D
R
M
T
S
P
S
V
Q
A
L
T
E
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
P109
M
K
D
H
M
T
S
P
M
A
I
T
V
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995814
323
36597
D109
M
S
L
N
R
S
R
D
R
D
I
T
A
H
Q
Honey Bee
Apis mellifera
XP_393125
262
30173
S117
M
K
D
K
M
N
L
S
R
G
R
D
R
D
N
Nematode Worm
Caenorhab. elegans
P83528
122
14016
L9
S
N
Y
R
Y
S
K
L
N
E
E
E
I
S
L
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
P109
M
K
E
H
M
S
S
P
G
T
K
T
R
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q946Y7
245
27703
G110
L
A
G
K
V
S
S
G
A
G
H
A
S
E
V
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
E110
I
P
L
E
E
T
V
E
N
S
T
L
N
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.5
99.6
96.4
N.A.
94.5
95.2
N.A.
78.8
91.3
76.4
75.3
N.A.
43.9
48
23.9
56.8
Protein Similarity:
100
75.6
99.6
97.6
N.A.
96.8
96.4
N.A.
84
95.6
87.4
86.7
N.A.
59.4
69.8
36.8
78
P-Site Identity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
66.6
33.3
N.A.
13.3
33.3
6.6
26.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
53.3
N.A.
20
53.3
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.9
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
7
0
0
0
19
0
7
7
0
57
7
38
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
63
0
0
0
0
7
0
7
7
7
0
7
7
% D
% Glu:
0
0
7
7
7
0
0
7
0
7
7
7
7
13
57
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
7
19
0
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
13
0
7
0
0
% I
% Lys:
0
69
0
13
0
0
7
0
0
0
7
0
0
0
0
% K
% Leu:
7
0
13
0
0
0
7
7
7
0
0
7
50
7
7
% L
% Met:
75
0
0
0
69
0
0
0
7
7
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
7
7
0
13
0
0
0
7
0
7
% N
% Pro:
0
7
0
0
0
7
0
19
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
44
0
0
0
0
0
0
50
0
0
0
13
% Q
% Arg:
0
0
0
13
7
0
7
0
13
0
7
7
13
0
0
% R
% Ser:
7
7
0
0
7
69
38
50
50
7
0
0
7
7
7
% S
% Thr:
0
0
0
0
0
19
13
0
0
7
7
19
0
19
0
% T
% Val:
0
0
0
0
7
0
7
0
0
44
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _