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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX6
All Species:
44.85
Human Site:
S56
Identified Species:
65.78
UniProt:
O43752
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43752
NP_005810.1
255
29176
S56
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Chimpanzee
Pan troglodytes
XP_001159596
200
22796
Q33
Q
R
W
T
E
L
L
Q
D
P
S
T
A
T
R
Rhesus Macaque
Macaca mulatta
XP_001114975
255
29127
S56
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Dog
Lupus familis
XP_547423
255
29118
S56
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
S56
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Rat
Rattus norvegicus
Q63635
255
29038
S56
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
S90
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Chicken
Gallus gallus
Q5ZL19
254
29137
S56
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Frog
Xenopus laevis
NP_001085148
254
29254
S56
E
L
R
N
N
L
R
S
I
E
W
D
L
E
D
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
S56
E
L
R
N
S
L
R
S
I
E
W
D
L
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995814
323
36597
D56
S
L
R
S
I
E
W
D
L
E
D
L
E
D
T
Honey Bee
Apis mellifera
XP_393125
262
30173
S64
E
L
R
K
A
L
R
S
I
E
W
D
L
D
D
Nematode Worm
Caenorhab. elegans
P83528
122
14016
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
S56
E
L
R
N
S
L
R
S
I
E
W
D
V
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q946Y7
245
27703
V57
C
G
S
I
E
W
Q
V
D
E
L
E
K
A
I
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
R57
E
T
I
V
D
L
D
R
S
I
I
V
M
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.5
99.6
96.4
N.A.
94.5
95.2
N.A.
78.8
91.3
76.4
75.3
N.A.
43.9
48
23.9
56.8
Protein Similarity:
100
75.6
99.6
97.6
N.A.
96.8
96.4
N.A.
84
95.6
87.4
86.7
N.A.
59.4
69.8
36.8
78
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
20
80
0
86.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
40
86.6
0
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.9
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
0
7
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
7
7
13
0
7
69
0
13
69
% D
% Glu:
75
0
0
0
13
7
0
0
0
82
0
7
7
63
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
7
0
0
0
69
7
7
0
0
0
7
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
0
7
7
0
% K
% Leu:
0
75
0
0
0
82
7
0
7
0
7
7
63
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
63
50
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% Q
% Arg:
0
7
75
0
0
0
69
7
0
0
0
0
0
0
13
% R
% Ser:
7
0
7
7
13
0
0
69
7
0
7
0
0
0
0
% S
% Thr:
0
7
0
7
0
0
0
0
0
0
0
7
0
7
7
% T
% Val:
0
0
0
7
0
0
0
7
0
0
0
7
7
0
0
% V
% Trp:
0
0
7
0
0
7
7
0
0
0
69
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _