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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX6
All Species:
21.21
Human Site:
S86
Identified Species:
31.11
UniProt:
O43752
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43752
NP_005810.1
255
29176
S86
N
L
D
A
T
E
L
S
I
R
K
A
F
I
T
Chimpanzee
Pan troglodytes
XP_001159596
200
22796
D63
S
I
E
W
D
L
E
D
L
D
E
T
I
N
I
Rhesus Macaque
Macaca mulatta
XP_001114975
255
29127
S86
N
L
D
A
T
E
L
S
I
R
K
A
F
I
T
Dog
Lupus familis
XP_547423
255
29118
S86
N
L
D
A
T
E
L
S
I
R
K
T
F
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
S86
N
L
D
A
T
E
L
S
I
R
K
A
F
I
T
Rat
Rattus norvegicus
Q63635
255
29038
S86
N
L
D
A
T
E
L
S
I
R
K
A
F
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
G120
N
L
D
A
A
E
L
G
V
R
K
A
F
I
T
Chicken
Gallus gallus
Q5ZL19
254
29137
G86
N
L
D
A
T
E
L
G
I
R
K
S
F
I
T
Frog
Xenopus laevis
NP_001085148
254
29254
R86
S
L
D
P
A
E
L
R
Q
R
K
A
F
I
N
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
A86
N
L
D
A
M
E
L
A
K
R
K
A
F
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995814
323
36597
H86
R
E
L
S
S
R
R
H
F
I
D
N
T
R
D
Honey Bee
Apis mellifera
XP_393125
262
30173
T94
K
I
D
N
K
E
L
T
V
Q
R
S
F
I
E
Nematode Worm
Caenorhab. elegans
P83528
122
14016
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
D86
R
I
E
P
S
D
L
D
T
R
R
L
F
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q946Y7
245
27703
W87
E
L
E
K
R
R
R
W
T
S
N
A
R
T
Q
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
L87
I
K
Q
Q
L
D
A
L
K
L
R
F
D
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.5
99.6
96.4
N.A.
94.5
95.2
N.A.
78.8
91.3
76.4
75.3
N.A.
43.9
48
23.9
56.8
Protein Similarity:
100
75.6
99.6
97.6
N.A.
96.8
96.4
N.A.
84
95.6
87.4
86.7
N.A.
59.4
69.8
36.8
78
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
80
86.6
60
80
N.A.
0
33.3
0
26.6
P-Site Similarity:
100
33.3
100
93.3
N.A.
100
100
N.A.
86.6
93.3
66.6
86.6
N.A.
13.3
73.3
0
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.9
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
13
0
7
7
0
0
0
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
63
0
7
13
0
13
0
7
7
0
7
0
7
% D
% Glu:
7
7
19
0
0
63
7
0
0
0
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
7
69
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
19
0
0
0
0
0
0
38
7
0
0
7
63
7
% I
% Lys:
7
7
0
7
7
0
0
0
13
0
57
0
0
0
0
% K
% Leu:
0
63
7
0
7
7
69
7
7
7
0
7
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
7
0
0
0
0
0
0
7
7
0
7
7
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
0
0
7
7
0
0
0
0
7
% Q
% Arg:
13
0
0
0
7
13
13
7
0
63
19
0
7
13
7
% R
% Ser:
13
0
0
7
13
0
0
32
0
7
0
13
0
0
0
% S
% Thr:
0
0
0
0
38
0
0
7
13
0
0
13
7
7
57
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
7
0
% V
% Trp:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _