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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX6
All Species:
46.06
Human Site:
T211
Identified Species:
67.56
UniProt:
O43752
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43752
NP_005810.1
255
29176
T211
F
S
H
E
L
E
S
T
Q
S
R
L
D
N
V
Chimpanzee
Pan troglodytes
XP_001159596
200
22796
T174
L
A
K
V
S
H
M
T
S
D
R
R
Q
W
C
Rhesus Macaque
Macaca mulatta
XP_001114975
255
29127
T211
F
S
H
E
L
E
S
T
Q
S
R
L
D
N
V
Dog
Lupus familis
XP_547423
255
29118
T211
F
S
H
E
L
E
S
T
Q
S
R
L
D
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKK1
255
28978
T211
F
S
H
E
L
E
S
T
Q
S
R
L
D
N
V
Rat
Rattus norvegicus
Q63635
255
29038
T211
F
S
H
E
L
E
S
T
Q
S
R
L
D
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515866
288
32736
T244
F
S
H
E
L
D
S
T
Q
S
R
L
D
N
V
Chicken
Gallus gallus
Q5ZL19
254
29137
T210
F
S
H
E
L
D
S
T
H
S
R
L
D
N
V
Frog
Xenopus laevis
NP_001085148
254
29254
A210
F
S
H
E
L
D
T
A
Q
S
R
M
D
N
V
Zebra Danio
Brachydanio rerio
NP_001017879
256
29159
T212
F
S
H
E
M
D
S
T
Q
S
R
L
D
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995814
323
36597
T279
F
G
N
E
F
D
T
T
E
S
K
L
D
T
T
Honey Bee
Apis mellifera
XP_393125
262
30173
T218
F
G
N
E
L
E
V
T
D
S
K
L
D
A
T
Nematode Worm
Caenorhab. elegans
P83528
122
14016
L96
K
M
A
K
L
T
H
L
E
D
E
S
S
Q
C
Sea Urchin
Strong. purpuratus
XP_780210
249
29158
T206
F
S
T
E
L
E
N
T
E
S
R
L
D
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q946Y7
245
27703
T201
L
D
T
E
M
D
S
T
K
N
R
L
E
F
V
Baker's Yeast
Sacchar. cerevisiae
Q03322
224
25798
N198
L
E
W
V
Y
E
K
N
K
E
K
Y
D
D
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.5
99.6
96.4
N.A.
94.5
95.2
N.A.
78.8
91.3
76.4
75.3
N.A.
43.9
48
23.9
56.8
Protein Similarity:
100
75.6
99.6
97.6
N.A.
96.8
96.4
N.A.
84
95.6
87.4
86.7
N.A.
59.4
69.8
36.8
78
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
86.6
73.3
86.6
N.A.
40
53.3
6.6
73.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
93.3
93.3
100
N.A.
73.3
66.6
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.9
47.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
7
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
0
7
0
0
0
38
0
0
7
13
0
0
82
7
0
% D
% Glu:
0
7
0
82
0
50
0
0
19
7
7
0
7
0
0
% E
% Phe:
75
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
13
0
0
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
57
0
0
7
7
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
7
7
0
0
7
0
13
0
19
0
0
0
0
% K
% Leu:
19
0
0
0
69
0
0
7
0
0
0
75
0
0
0
% L
% Met:
0
7
0
0
13
0
7
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
13
0
0
0
7
7
0
7
0
0
0
57
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
0
0
0
7
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
75
7
0
0
0
% R
% Ser:
0
63
0
0
7
0
57
0
7
75
0
7
7
0
0
% S
% Thr:
0
0
13
0
0
7
13
82
0
0
0
0
0
7
13
% T
% Val:
0
0
0
13
0
0
7
0
0
0
0
0
0
0
69
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _