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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNGR2
All Species:
24.85
Human Site:
S194
Identified Species:
49.7
UniProt:
O43760
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43760
NP_004701.1
224
24810
S194
D
P
N
T
A
Y
A
S
Y
P
G
A
S
V
D
Chimpanzee
Pan troglodytes
XP_001145116
252
27747
S222
T
P
D
P
N
T
A
S
Y
P
G
A
S
V
D
Rhesus Macaque
Macaca mulatta
XP_001107757
224
24760
S194
D
P
N
T
A
Y
A
S
Y
P
G
A
S
V
D
Dog
Lupus familis
XP_851305
459
50768
S429
D
P
S
T
A
Y
A
S
Y
P
G
A
S
V
D
Cat
Felis silvestris
Mouse
Mus musculus
O55101
224
24759
S194
D
P
N
T
A
Y
A
S
Y
P
S
A
S
V
E
Rat
Rattus norvegicus
O54980
224
24692
S194
D
P
T
T
A
Y
A
S
Y
P
S
A
S
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512157
220
24248
P190
P
T
P
E
P
G
T
P
Y
P
N
V
A
V
D
Chicken
Gallus gallus
NP_001007835
230
25156
P195
T
D
P
N
A
A
Y
P
G
Y
P
T
G
S
G
Frog
Xenopus laevis
NP_001086788
217
24253
S188
D
P
T
Q
D
T
S
S
Y
P
S
Y
P
A
S
Zebra Danio
Brachydanio rerio
XP_696934
235
25748
T196
L
S
S
P
Y
P
S
T
Y
T
P
P
T
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76735
247
26774
T195
E
H
F
G
Q
V
S
T
D
V
Q
D
G
Y
G
Sea Urchin
Strong. purpuratus
XP_001177627
234
25324
G192
D
Q
P
T
P
Y
P
G
T
T
A
T
S
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.5
96.8
43.3
N.A.
88.8
87.9
N.A.
70
48.2
59.3
49.7
N.A.
N.A.
N.A.
24.7
41.4
Protein Similarity:
100
78.5
98.2
45.3
N.A.
92.8
91.9
N.A.
81.6
60.8
71.4
63.8
N.A.
N.A.
N.A.
46.9
58.5
P-Site Identity:
100
66.6
100
93.3
N.A.
86.6
80
N.A.
26.6
6.6
33.3
6.6
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
100
73.3
100
100
N.A.
93.3
86.6
N.A.
33.3
6.6
40
33.3
N.A.
N.A.
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
9
50
0
0
0
9
50
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
9
9
0
9
0
0
0
9
0
0
9
0
0
42
% D
% Glu:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
17
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
0
9
9
0
34
0
17
0
25
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
25
9
9
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
9
59
25
17
17
9
9
17
0
67
17
9
9
0
9
% P
% Gln:
0
9
0
9
9
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
17
0
0
0
25
59
0
0
25
0
59
9
9
% S
% Thr:
17
9
17
50
0
17
9
17
9
17
0
17
9
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
9
0
9
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
50
9
0
75
9
0
9
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _