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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYNGR2 All Species: 23.33
Human Site: Y192 Identified Species: 46.67
UniProt: O43760 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43760 NP_004701.1 224 24810 Y192 T P D P N T A Y A S Y P G A S
Chimpanzee Pan troglodytes XP_001145116 252 27747 T220 D P T P D P N T A S Y P G A S
Rhesus Macaque Macaca mulatta XP_001107757 224 24760 Y192 T P D P N T A Y A S Y P G A S
Dog Lupus familis XP_851305 459 50768 Y427 T P D P S T A Y A S Y P G A S
Cat Felis silvestris
Mouse Mus musculus O55101 224 24759 Y192 T P D P N T A Y A S Y P S A S
Rat Rattus norvegicus O54980 224 24692 Y192 T P D P T T A Y A S Y P S A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512157 220 24248 G188 A D P T P E P G T P Y P N V A
Chicken Gallus gallus NP_001007835 230 25156 A193 F A T D P N A A Y P G Y P T G
Frog Xenopus laevis NP_001086788 217 24253 T186 Y V D P T Q D T S S Y P S Y P
Zebra Danio Brachydanio rerio XP_696934 235 25748 P194 P D L S S P Y P S T Y T P P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O76735 247 26774 V193 Y D E H F G Q V S T D V Q D G
Sea Urchin Strong. purpuratus XP_001177627 234 25324 Y190 P S D Q P T P Y P G T T A T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.5 96.8 43.3 N.A. 88.8 87.9 N.A. 70 48.2 59.3 49.7 N.A. N.A. N.A. 24.7 41.4
Protein Similarity: 100 78.5 98.2 45.3 N.A. 92.8 91.9 N.A. 81.6 60.8 71.4 63.8 N.A. N.A. N.A. 46.9 58.5
P-Site Identity: 100 60 100 93.3 N.A. 93.3 86.6 N.A. 13.3 6.6 33.3 6.6 N.A. N.A. N.A. 0 26.6
P-Site Similarity: 100 66.6 100 100 N.A. 93.3 86.6 N.A. 20 6.6 40 33.3 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 50 9 50 0 0 0 9 50 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 25 59 9 9 0 9 0 0 0 9 0 0 9 0 % D
% Glu: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 9 0 9 9 0 34 0 17 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 25 9 9 0 0 0 0 0 9 0 0 % N
% Pro: 17 50 9 59 25 17 17 9 9 17 0 67 17 9 9 % P
% Gln: 0 0 0 9 0 9 9 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 9 17 0 0 0 25 59 0 0 25 0 59 % S
% Thr: 42 0 17 9 17 50 0 17 9 17 9 17 0 17 9 % T
% Val: 0 9 0 0 0 0 0 9 0 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 0 0 0 0 0 9 50 9 0 75 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _