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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYNGR3 All Species: 14.24
Human Site: S19 Identified Species: 28.48
UniProt: O43761 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43761 NP_004200.2 229 24555 S19 G A A L D P V S F A R R P Q T
Chimpanzee Pan troglodytes XP_523480 239 25809 T29 G Q P G T T P T R L L V S D A
Rhesus Macaque Macaca mulatta XP_001082714 212 22510 T23 G P F A E E R T P P V C P P G
Dog Lupus familis XP_547182 198 21377 G16 F G P I V N E G Y V N T D S G
Cat Felis silvestris
Mouse Mus musculus Q8R191 229 24542 S19 G A A F D P V S F A R R P Q T
Rat Rattus norvegicus Q62876 234 25650 T19 G G A F D P Y T L V R Q P H T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520071 132 14496
Chicken Gallus gallus NP_001007835 230 25156 D19 G G A V D P L D F L K Q P Q T
Frog Xenopus laevis NP_001088783 231 25488 T19 G G A F D P Q T F I R Q P H T
Zebra Danio Brachydanio rerio NP_001018427 228 25418 A20 G A A F D P F A F I Q Q P Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O76735 247 26774 T20 G A N F D K N T F F K K P T V
Sea Urchin Strong. purpuratus XP_001177627 234 25324 D19 G K P F D V L D Y I K K P S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.9 33.6 84.2 N.A. 93.8 50.8 N.A. 41 69.1 48.9 58.9 N.A. N.A. N.A. 28.3 40.6
Protein Similarity: 100 79 43.2 85.1 N.A. 96 64 N.A. 46.7 81.3 65.3 72.9 N.A. N.A. N.A. 44.1 58.1
P-Site Identity: 100 6.6 13.3 0 N.A. 93.3 46.6 N.A. 0 53.3 53.3 60 N.A. N.A. N.A. 33.3 20
P-Site Similarity: 100 13.3 26.6 13.3 N.A. 93.3 60 N.A. 0 80 66.6 80 N.A. N.A. N.A. 53.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 50 9 0 0 0 9 0 17 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 67 0 0 17 0 0 0 0 9 9 0 % D
% Glu: 0 0 0 0 9 9 9 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 9 50 0 0 9 0 50 9 0 0 0 0 0 % F
% Gly: 84 34 0 9 0 0 0 9 0 0 0 0 0 0 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 25 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 9 0 0 0 0 25 17 0 0 0 % K
% Leu: 0 0 0 9 0 0 17 0 9 17 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 9 9 0 0 0 9 0 0 0 0 % N
% Pro: 0 9 25 0 0 50 9 0 9 9 0 0 75 9 0 % P
% Gln: 0 9 0 0 0 0 9 0 0 0 9 34 0 34 0 % Q
% Arg: 0 0 0 0 0 0 9 0 9 0 34 17 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 17 0 0 0 0 9 17 0 % S
% Thr: 0 0 0 0 9 9 0 42 0 0 0 9 0 9 50 % T
% Val: 0 0 0 9 9 9 17 0 0 17 9 9 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _