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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNGR3
All Species:
23.94
Human Site:
T182
Identified Species:
47.88
UniProt:
O43761
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43761
NP_004200.2
229
24555
T182
T
D
M
S
L
F
A
T
E
Q
L
S
T
G
A
Chimpanzee
Pan troglodytes
XP_523480
239
25809
T192
T
D
M
S
L
F
A
T
E
Q
L
S
T
G
A
Rhesus Macaque
Macaca mulatta
XP_001082714
212
22510
T165
D
L
G
F
S
V
A
T
E
Q
L
S
A
G
A
Dog
Lupus familis
XP_547182
198
21377
T151
T
D
M
S
L
F
A
T
E
Q
L
G
T
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R191
229
24542
T182
T
D
M
S
L
F
A
T
D
Q
L
G
T
G
A
Rat
Rattus norvegicus
Q62876
234
25650
S182
G
A
D
S
A
L
F
S
Q
D
Y
M
D
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520071
132
14496
W86
S
G
L
W
S
F
L
W
F
V
G
F
C
F
L
Chicken
Gallus gallus
NP_001007835
230
25156
T183
T
D
M
S
L
F
A
T
D
Q
F
A
T
D
P
Frog
Xenopus laevis
NP_001088783
231
25488
S182
G
S
D
S
A
L
F
S
Q
D
Y
M
D
P
S
Zebra Danio
Brachydanio rerio
NP_001018427
228
25418
T182
G
T
D
M
T
L
F
T
T
E
H
I
D
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76735
247
26774
E183
E
G
N
Q
A
T
H
E
P
N
Y
D
E
H
F
Sea Urchin
Strong. purpuratus
XP_001177627
234
25324
S180
S
A
S
A
F
A
P
S
F
E
P
S
D
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
33.6
84.2
N.A.
93.8
50.8
N.A.
41
69.1
48.9
58.9
N.A.
N.A.
N.A.
28.3
40.6
Protein Similarity:
100
79
43.2
85.1
N.A.
96
64
N.A.
46.7
81.3
65.3
72.9
N.A.
N.A.
N.A.
44.1
58.1
P-Site Identity:
100
100
53.3
93.3
N.A.
86.6
6.6
N.A.
6.6
66.6
6.6
13.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
53.3
93.3
N.A.
93.3
26.6
N.A.
20
80
26.6
20
N.A.
N.A.
N.A.
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
25
9
50
0
0
0
0
9
9
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
42
25
0
0
0
0
0
17
17
0
9
34
9
0
% D
% Glu:
9
0
0
0
0
0
0
9
34
17
0
0
9
0
0
% E
% Phe:
0
0
0
9
9
50
25
0
17
0
9
9
0
9
9
% F
% Gly:
25
17
9
0
0
0
0
0
0
0
9
17
0
50
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
9
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
0
42
25
9
0
0
0
42
0
0
0
9
% L
% Met:
0
0
42
9
0
0
0
0
0
0
0
17
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
9
0
0
17
17
% P
% Gln:
0
0
0
9
0
0
0
0
17
50
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
9
9
59
17
0
0
25
0
0
0
34
0
0
17
% S
% Thr:
42
9
0
0
9
9
0
59
9
0
0
0
42
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _