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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYNGR3 All Species: 22.03
Human Site: Y224 Identified Species: 44.06
UniProt: O43761 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43761 NP_004200.2 229 24555 Y224 L D T S P K G Y Q V P A Y _ _
Chimpanzee Pan troglodytes XP_523480 239 25809 Y234 L D T S P K G Y Q V P A Y _ _
Rhesus Macaque Macaca mulatta XP_001082714 212 22510 Y207 L D T S P K G Y Q V P A Y _ _
Dog Lupus familis XP_547182 198 21377 Y193 L D T S P K G Y Q V P A Y _ _
Cat Felis silvestris
Mouse Mus musculus Q8R191 229 24542 Y224 L D T S S K G Y Q V P A Y _ _
Rat Rattus norvegicus Q62876 234 25650 A224 H P A N A F D A E P Q G Y Q S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520071 132 14496
Chicken Gallus gallus NP_001007835 230 25156 Y225 S D T N P K G Y Q V P A Y _ _
Frog Xenopus laevis NP_001088783 231 25488 H224 E A Y D A G S H G Y Q T Q D Y
Zebra Danio Brachydanio rerio NP_001018427 228 25418
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O76735 247 26774 G225 P Q S S Y Q S G A A P Q T M Q
Sea Urchin Strong. purpuratus XP_001177627 234 25324 A222 S G D P G F S A P P S Q A Q Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.9 33.6 84.2 N.A. 93.8 50.8 N.A. 41 69.1 48.9 58.9 N.A. N.A. N.A. 28.3 40.6
Protein Similarity: 100 79 43.2 85.1 N.A. 96 64 N.A. 46.7 81.3 65.3 72.9 N.A. N.A. N.A. 44.1 58.1
P-Site Identity: 100 100 100 100 N.A. 92.3 6.6 N.A. 0 84.6 0 0 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 92.3 20 N.A. 0 92.3 13.3 0 N.A. N.A. N.A. 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 17 0 0 17 9 9 0 50 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 9 9 0 0 9 0 0 0 0 0 0 9 0 % D
% Glu: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 9 50 9 9 0 0 9 0 0 0 % G
% His: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % K
% Leu: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 0 9 42 0 0 0 9 17 59 0 0 0 0 % P
% Gln: 0 9 0 0 0 9 0 0 50 0 17 17 9 17 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 0 9 50 9 0 25 0 0 0 9 0 0 0 9 % S
% Thr: 0 0 50 0 0 0 0 0 0 0 0 9 9 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 9 0 0 50 0 9 0 0 59 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 50 % _