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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNGR3
All Species:
19.39
Human Site:
Y48
Identified Species:
38.79
UniProt:
O43761
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43761
NP_004200.2
229
24555
Y48
G
P
I
V
N
E
G
Y
V
N
T
D
S
G
P
Chimpanzee
Pan troglodytes
XP_523480
239
25809
Y58
G
E
T
Q
D
G
G
Y
V
N
P
D
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001082714
212
22510
F52
H
G
D
L
A
G
G
F
L
R
M
A
S
I
S
Dog
Lupus familis
XP_547182
198
21377
L45
R
F
G
I
A
L
G
L
G
A
F
L
A
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R191
229
24542
Y48
G
P
I
V
N
E
G
Y
V
N
S
D
S
G
P
Rat
Rattus norvegicus
Q62876
234
25650
Y48
G
S
I
V
N
E
G
Y
L
N
N
P
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520071
132
14496
Chicken
Gallus gallus
NP_001007835
230
25156
Y48
G
S
I
V
N
E
C
Y
M
N
K
D
G
T
D
Frog
Xenopus laevis
NP_001088783
231
25488
Y48
G
C
I
I
N
E
G
Y
I
N
S
P
T
E
E
Zebra Danio
Brachydanio rerio
NP_001018427
228
25418
Y49
G
S
I
I
N
E
G
Y
V
N
H
G
S
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76735
247
26774
W49
Y
S
V
S
K
G
G
W
H
K
P
S
D
A
I
Sea Urchin
Strong. purpuratus
XP_001177627
234
25324
E48
A
C
I
S
A
E
K
E
Y
S
F
G
S
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.9
33.6
84.2
N.A.
93.8
50.8
N.A.
41
69.1
48.9
58.9
N.A.
N.A.
N.A.
28.3
40.6
Protein Similarity:
100
79
43.2
85.1
N.A.
96
64
N.A.
46.7
81.3
65.3
72.9
N.A.
N.A.
N.A.
44.1
58.1
P-Site Identity:
100
60
13.3
6.6
N.A.
93.3
53.3
N.A.
0
53.3
46.6
60
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
66.6
33.3
20
N.A.
100
60
N.A.
0
60
73.3
66.6
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
25
0
0
0
0
9
0
9
9
9
9
% A
% Cys:
0
17
0
0
0
0
9
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
9
0
9
0
0
0
0
0
0
34
9
0
9
% D
% Glu:
0
9
0
0
0
59
0
9
0
0
0
0
9
17
17
% E
% Phe:
0
9
0
0
0
0
0
9
0
0
17
0
0
0
0
% F
% Gly:
59
9
9
0
0
25
75
0
9
0
0
17
9
25
0
% G
% His:
9
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% H
% Ile:
0
0
59
25
0
0
0
0
9
0
0
0
0
9
9
% I
% Lys:
0
0
0
0
9
0
9
0
0
9
9
0
0
0
0
% K
% Leu:
0
0
0
9
0
9
0
9
17
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
50
0
0
0
0
59
9
0
0
0
0
% N
% Pro:
0
17
0
0
0
0
0
0
0
0
17
17
0
0
25
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% R
% Ser:
0
34
0
17
0
0
0
0
0
9
17
9
50
0
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
9
0
9
9
0
% T
% Val:
0
0
9
34
0
0
0
0
34
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
59
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _