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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX2
All Species:
26.06
Human Site:
S163
Identified Species:
47.78
UniProt:
O43763
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43763
NP_057254.1
284
30251
S163
K
R
K
K
P
R
T
S
F
S
R
S
Q
V
L
Chimpanzee
Pan troglodytes
XP_001161223
284
30206
S163
K
R
K
K
P
R
T
S
F
S
R
S
Q
V
L
Rhesus Macaque
Macaca mulatta
XP_001110250
284
30204
S163
K
R
K
K
P
R
T
S
F
S
R
S
Q
V
L
Dog
Lupus familis
XP_855075
284
30159
S163
K
R
K
K
P
R
T
S
F
S
R
S
Q
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61663
284
30342
S163
K
R
K
K
P
R
T
S
F
S
R
S
Q
V
L
Rat
Rattus norvegicus
O88181
384
41445
A235
K
P
R
K
A
R
T
A
F
S
D
H
Q
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
S216
K
K
K
K
P
R
T
S
F
T
R
L
Q
I
C
Chicken
Gallus gallus
O93367
297
32351
S178
K
R
K
K
P
R
T
S
F
S
R
V
Q
I
C
Frog
Xenopus laevis
Q8JJ64
306
34004
V184
R
K
K
K
T
R
T
V
F
S
R
S
Q
V
F
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
V176
R
K
K
K
T
R
T
V
F
S
R
S
Q
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
V474
R
K
K
K
T
R
T
V
F
S
R
A
Q
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
D55
G
R
C
K
S
S
L
D
Q
A
K
E
S
P
I
Sea Urchin
Strong. purpuratus
Q26656
405
44721
V259
K
K
K
K
T
R
T
V
F
S
R
S
Q
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
91.1
N.A.
92.9
25.5
N.A.
46.7
57.5
27.1
22.5
N.A.
21.4
N.A.
26
25.6
Protein Similarity:
100
100
99.3
93.6
N.A.
95
33.8
N.A.
55.2
65.6
37.9
33
N.A.
28.2
N.A.
36.6
36.5
P-Site Identity:
100
100
100
100
N.A.
100
46.6
N.A.
66.6
80
66.6
66.6
N.A.
60
N.A.
13.3
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
86.6
86.6
80
80
N.A.
80
N.A.
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
8
0
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
16
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
31
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% I
% Lys:
70
39
85
100
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
0
54
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
93
0
0
% Q
% Arg:
24
54
8
0
0
93
0
0
0
0
85
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
54
0
85
0
62
8
0
0
% S
% Thr:
0
0
0
0
31
0
93
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
31
0
0
0
8
0
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _