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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGTA All Species: 12.42
Human Site: S77 Identified Species: 21.03
UniProt: O43765 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43765 NP_003012.1 313 34063 S77 E M P Q D L R S P A R T P P S
Chimpanzee Pan troglodytes XP_526906 304 33438 N76 N D V L P L S N S V P E D V G
Rhesus Macaque Macaca mulatta XP_001117755 382 40889 S146 E V P Q D L R S P A R T P P S
Dog Lupus familis XP_542185 313 34250 S77 E V P Q D L R S P E R T P P S
Cat Felis silvestris
Mouse Mus musculus Q8BJU0 315 34304 R77 Q E M P Q D P R A P D R T P P
Rat Rattus norvegicus O70593 314 34139 G77 E M P Q D P R G P D R T P P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507204 312 33825 S77 L P Y I P L N S Q S S P P S D
Chicken Gallus gallus NP_001026550 313 33751 S77 P E H I R A N S E P V T P S E
Frog Xenopus laevis NP_001084568 312 33946 L77 T P Q A N S G L A S P S D E D
Zebra Danio Brachydanio rerio NP_997929 320 34189 F77 G T T Q E N T F V T T G S P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393400 299 32833 P76 Y L A P E A T P E A K A E A E
Nematode Worm Caenorhab. elegans NP_494893 337 36449 E91 A E G L P E G E S A L P T P S
Sea Urchin Strong. purpuratus XP_786841 356 38124 T77 G G Q Q P D V T Q V A Q S S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12118 346 37200 S78 S A S R V P E S N K K D D A E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.1 81.6 95.8 N.A. 88.2 88.5 N.A. 84.3 81.1 73.8 68.1 N.A. N.A. 44.4 40 39.8
Protein Similarity: 100 71.5 81.9 97.7 N.A. 94.5 94.2 N.A. 90.7 88.5 84.9 80 N.A. N.A. 60.3 54.9 59.2
P-Site Identity: 100 6.6 93.3 86.6 N.A. 6.6 80 N.A. 20 20 0 13.3 N.A. N.A. 6.6 20 6.6
P-Site Similarity: 100 13.3 100 93.3 N.A. 13.3 80 N.A. 26.6 20 20 20 N.A. N.A. 26.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 8 0 15 0 0 15 29 8 8 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 29 15 0 0 0 8 8 8 22 0 15 % D
% Glu: 29 22 0 0 15 8 8 8 15 8 0 8 8 8 22 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 15 8 8 0 0 0 15 8 0 0 0 8 0 0 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 15 0 0 0 0 % K
% Leu: 8 8 0 15 0 36 0 8 0 0 8 0 0 0 0 % L
% Met: 0 15 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 8 15 8 8 0 0 0 0 0 0 % N
% Pro: 8 15 29 15 29 15 8 8 29 15 15 15 43 50 8 % P
% Gln: 8 0 15 43 8 0 0 0 15 0 0 8 0 0 0 % Q
% Arg: 0 0 0 8 8 0 29 8 0 0 29 8 0 0 0 % R
% Ser: 8 0 8 0 0 8 8 43 15 15 8 8 15 22 36 % S
% Thr: 8 8 8 0 0 0 15 8 0 8 8 36 15 0 0 % T
% Val: 0 15 8 0 8 0 8 0 8 15 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _