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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIAS
All Species:
45.76
Human Site:
T196
Identified Species:
83.89
UniProt:
O43766
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43766
NP_006850.2
372
41911
T196
G
A
E
H
I
A
K
T
V
S
Y
L
K
E
R
Chimpanzee
Pan troglodytes
XP_526552
372
41906
T196
G
A
E
H
I
A
K
T
V
S
Y
L
K
E
R
Rhesus Macaque
Macaca mulatta
XP_001091994
372
41800
T196
G
A
E
H
I
A
K
T
V
S
Y
L
K
E
R
Dog
Lupus familis
XP_536255
373
41947
T196
G
A
E
H
F
A
K
T
V
S
Y
L
K
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99M04
373
41861
T195
G
A
E
H
I
A
K
T
V
S
C
L
K
E
R
Rat
Rattus norvegicus
Q5XIH4
373
41855
T195
G
A
E
H
I
A
K
T
V
S
C
L
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512706
391
44185
T207
G
A
E
H
F
A
R
T
V
S
H
L
K
E
R
Chicken
Gallus gallus
XP_423226
385
43052
T209
G
A
E
H
F
A
K
T
V
S
H
L
K
E
R
Frog
Xenopus laevis
NP_001085534
372
41784
T196
G
A
E
H
I
A
Q
T
V
S
M
L
K
E
R
Zebra Danio
Brachydanio rerio
NP_001103871
397
44192
T216
G
A
E
H
F
A
K
T
V
S
N
I
K
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524183
377
42715
T193
G
S
E
H
I
A
E
T
V
R
E
I
K
A
R
Honey Bee
Apis mellifera
XP_625022
367
41898
E188
G
G
A
N
H
I
A
E
T
V
K
E
I
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32875
414
46229
T240
G
A
N
H
L
A
E
T
V
R
K
I
K
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.9
93.8
N.A.
90
90.8
N.A.
80.8
83.3
82.2
73.3
N.A.
62.3
63.1
N.A.
N.A.
Protein Similarity:
100
99.7
99.1
96.2
N.A.
94.9
95.7
N.A.
87.4
88.8
89.7
83.1
N.A.
75.5
75.2
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
86.6
86.6
80
N.A.
60
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
86.6
N.A.
80
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
62.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
85
8
0
0
93
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
85
0
0
0
16
8
0
0
8
8
0
77
0
% E
% Phe:
0
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
100
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
93
8
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
0
0
54
8
0
0
0
0
0
24
8
0
0
% I
% Lys:
0
0
0
0
0
0
62
0
0
0
16
0
93
8
16
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
70
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
16
0
0
0
0
85
% R
% Ser:
0
8
0
0
0
0
0
0
0
77
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
93
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
93
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _