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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A20 All Species: 29.7
Human Site: S205 Identified Species: 43.56
UniProt: O43772 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43772 NP_000378.1 301 32944 S205 T P E G K R V S E L S A P R I
Chimpanzee Pan troglodytes XP_516446 380 41666 S205 T P E G K R V S E L S A P R I
Rhesus Macaque Macaca mulatta XP_001111751 301 33022 S205 T P E G K R V S E L S V P R I
Dog Lupus familis XP_863142 301 32732 S205 T P E G K S V S E L S V P R I
Cat Felis silvestris
Mouse Mus musculus Q9Z2Z6 301 33008 S205 T P E G K S V S D L S V P R I
Rat Rattus norvegicus P97521 301 33135 H205 T P Q G K S V H D L S V P R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414400 301 32821 S205 T P E G K S V S D L S V P R I
Frog Xenopus laevis NP_001088580 301 32722 S205 T P E G H S V S E L S V P K I
Zebra Danio Brachydanio rerio A4QNX2 288 31518 G200 T T E N Q R P G W P V V L L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQG4 306 32934 Q211 K S K S E T G Q I S T A S T I
Honey Bee Apis mellifera XP_624739 290 31667 G200 S S E E G K L G I L Q T I M A
Nematode Worm Caenorhab. elegans Q27257 312 33116 T202 S G E G A Q R T L S P G A T L
Sea Urchin Strong. purpuratus XP_787461 298 31816 S204 T P E G Q K P S D L S V L R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93XM7 300 31004 K199 F A A Y E A F K R F L A G G S
Baker's Yeast Sacchar. cerevisiae Q12289 327 34736 D230 N S R Q P R Q D A G K D E P V
Red Bread Mold Neurospora crassa Q01356 363 39383 N238 S K W F R G R N E R A L L K R
Conservation
Percent
Protein Identity: 100 77.6 99 96.3 N.A. 93 90.3 N.A. N.A. 86 84 35.8 N.A. 50.6 58.4 53.5 64.7
Protein Similarity: 100 78.1 99.3 97.6 N.A. 95.6 94.6 N.A. N.A. 93 91.3 52.1 N.A. 69.6 73 67.9 75
P-Site Identity: 100 100 93.3 86.6 N.A. 80 60 N.A. N.A. 80 73.3 20 N.A. 13.3 13.3 13.3 53.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 80 N.A. N.A. 86.6 80 26.6 N.A. 33.3 33.3 40 80
Percent
Protein Identity: N.A. N.A. N.A. 39.2 34.2 27.5
Protein Similarity: N.A. N.A. N.A. 53.1 51.6 44
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 7 7 0 0 7 0 7 25 7 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 25 0 0 7 0 0 0 % D
% Glu: 0 0 69 7 13 0 0 0 38 0 0 0 7 0 0 % E
% Phe: 7 0 0 7 0 0 7 0 0 7 0 0 0 0 0 % F
% Gly: 0 7 0 63 7 7 7 13 0 7 0 7 7 7 0 % G
% His: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 13 0 0 0 7 0 50 % I
% Lys: 7 7 7 0 44 13 0 7 0 0 7 0 0 13 0 % K
% Leu: 0 0 0 0 0 0 7 0 7 63 7 7 19 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 57 0 0 7 0 13 0 0 7 7 0 50 7 0 % P
% Gln: 0 0 7 7 13 7 7 7 0 0 7 0 0 0 0 % Q
% Arg: 0 0 7 0 7 32 13 0 7 7 0 0 0 50 7 % R
% Ser: 19 19 0 7 0 32 0 50 0 13 57 0 7 0 7 % S
% Thr: 63 7 0 0 0 7 0 7 0 0 7 7 0 13 0 % T
% Val: 0 0 0 0 0 0 50 0 0 0 7 50 0 0 19 % V
% Trp: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _