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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT86
All Species:
3.03
Human Site:
S458
Identified Species:
7.41
UniProt:
O43790
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43790
NP_002275.1
486
53501
S458
T
R
V
S
S
V
P
S
N
S
N
V
V
V
G
Chimpanzee
Pan troglodytes
A5A6M8
592
62520
V565
S
S
G
R
G
L
G
V
G
F
G
S
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001093214
505
54939
N458
S
V
C
S
A
P
C
N
G
N
V
A
V
S
T
Dog
Lupus familis
XP_543656
485
53150
C458
S
R
V
C
S
A
P
C
S
G
N
L
V
V
G
Cat
Felis silvestris
Mouse
Mus musculus
P97861
486
53233
C458
T
R
V
C
S
A
P
C
S
G
N
V
V
V
G
Rat
Rattus norvegicus
Q6IG05
542
59008
F512
T
G
L
G
G
S
G
F
T
T
S
S
S
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514791
516
55880
S460
G
V
C
S
A
P
C
S
G
N
L
V
V
S
T
Chicken
Gallus gallus
O93532
492
53785
S465
A
L
G
A
G
M
G
S
G
A
L
G
F
S
S
Frog
Xenopus laevis
P16878
513
55433
G483
S
Y
G
A
G
G
F
G
N
S
S
A
R
F
G
Zebra Danio
Brachydanio rerio
Q6NWF6
520
57741
G467
G
Y
S
S
G
L
S
G
G
Y
G
G
G
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.4
89.6
89.5
N.A.
87.2
47.7
N.A.
79.2
49.5
48.1
44.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.1
92
94
N.A.
93.6
63.2
N.A.
86
65.8
63.5
62.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
53.3
N.A.
66.6
13.3
N.A.
26.6
6.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
40
73.3
N.A.
73.3
33.3
N.A.
40
26.6
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
20
20
0
0
0
10
0
20
0
0
0
% A
% Cys:
0
0
20
20
0
0
20
20
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
10
0
0
10
10
0
% F
% Gly:
20
10
30
10
50
10
30
20
50
20
20
20
20
10
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
0
0
20
0
0
0
0
20
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
20
20
30
0
0
0
0
% N
% Pro:
0
0
0
0
0
20
30
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
30
0
10
0
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
40
10
10
40
30
10
10
30
20
20
20
20
10
30
20
% S
% Thr:
30
0
0
0
0
0
0
0
10
10
0
0
0
0
20
% T
% Val:
0
20
30
0
0
10
0
10
0
0
10
30
50
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _