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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPOP
All Species:
34.55
Human Site:
S236
Identified Species:
63.33
UniProt:
O43791
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43791
NP_001007227.1
374
42132
S236
F
E
H
E
M
E
E
S
K
K
N
R
V
E
I
Chimpanzee
Pan troglodytes
XP_001168292
392
44160
S236
F
E
H
E
M
E
E
S
K
K
N
R
V
E
I
Rhesus Macaque
Macaca mulatta
XP_001094028
392
44244
S236
F
E
H
E
M
E
E
S
K
K
N
R
V
E
I
Dog
Lupus familis
XP_865058
415
46627
S236
F
E
H
E
M
E
E
S
K
K
N
R
V
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q2M2N2
392
44655
C236
F
E
H
E
M
E
E
C
T
K
N
R
V
E
I
Rat
Rattus norvegicus
NP_001127919
392
44725
C236
F
E
H
E
M
E
E
C
T
K
N
R
V
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509972
374
42178
S236
F
E
H
E
M
E
E
S
K
K
N
Q
M
E
I
Chicken
Gallus gallus
XP_423281
374
42132
S236
F
E
H
E
M
E
E
S
K
K
N
R
V
E
I
Frog
Xenopus laevis
Q7ZX06
374
42136
S236
F
E
H
E
M
E
E
S
K
K
N
R
V
E
I
Zebra Danio
Brachydanio rerio
Q7T330
374
42116
S236
F
E
H
E
M
E
E
S
K
K
N
R
V
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFP2
829
89649
R691
F
E
H
E
M
E
E
R
K
L
N
R
V
A
I
Honey Bee
Apis mellifera
XP_395294
396
44485
R258
F
E
H
E
M
E
E
R
K
Q
N
R
V
D
I
Nematode Worm
Caenorhab. elegans
P34568
451
51044
S307
F
E
H
H
M
Q
E
S
D
T
N
M
T
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
95.4
90.1
N.A.
79.5
79.5
N.A.
84.7
99.7
98.6
97.3
N.A.
36.6
76.5
54.7
N.A.
Protein Similarity:
100
95.4
95.4
90.1
N.A.
88.5
88.5
N.A.
93
100
99.4
98.9
N.A.
41.1
85.8
68.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
86.6
100
100
100
N.A.
80
80
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
100
100
100
100
N.A.
80
93.3
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
100
0
93
0
93
100
0
0
0
0
0
0
77
0
% E
% Phe:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
100
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
93
% I
% Lys:
0
0
0
0
0
0
0
0
77
77
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
100
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
0
85
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
16
8
0
0
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
85
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _