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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A17 All Species: 35.15
Human Site: T127 Identified Species: 59.49
UniProt: O43808 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43808 NP_006349.1 307 34567 T127 T P L W V V N T R L K L Q G A
Chimpanzee Pan troglodytes XP_515260 425 48646 T245 T P L W V V N T R L K L Q G A
Rhesus Macaque Macaca mulatta XP_001102293 307 34540 T127 T P L W V V N T R L K L Q G A
Dog Lupus familis XP_531726 307 34516 T127 T P L W V V N T R L K L Q G A
Cat Felis silvestris
Mouse Mus musculus O70579 307 34394 T127 T P L W V V N T R L K L Q G A
Rat Rattus norvegicus P56499 308 33996 A131 G A M A V T C A Q P T D V V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508103 244 28142 A71 T R L K L Q G A K F R N E D I
Chicken Gallus gallus XP_416242 335 37224 T155 T P L W V V N T R L K L Q G A
Frog Xenopus laevis NP_001088333 310 34543 T134 T P L W V V N T R L K L Q G A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728982 314 34398 T135 T P F W V V N T R L R M R N V
Honey Bee Apis mellifera XP_623636 308 34915 T132 T P L W V V N T R L K M R G I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783345 276 31233 Q103 R L K M Q G V Q F K T K H F R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39953 335 36942 W160 T V A T N P I W V V K T R L M
Red Bread Mold Neurospora crassa Q7S2H8 333 36079 D153 T A V T Y P L D L L R T R F A
Conservation
Percent
Protein Identity: 100 69.4 98 96.7 N.A. 95.4 25.6 N.A. 64.1 82.3 76.1 N.A. N.A. 47.7 49.3 N.A. 47.2
Protein Similarity: 100 71 99.3 99 N.A. 98 42.8 N.A. 69.7 87.4 88.3 N.A. N.A. 66.5 66.8 N.A. 59.2
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 13.3 100 100 N.A. N.A. 60 80 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 40 100 100 N.A. N.A. 80 93.3 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.2 22.5
Protein Similarity: N.A. N.A. N.A. N.A. 43.5 37.8
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 8 0 0 0 15 0 0 0 0 0 0 58 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 8 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 8 8 0 0 0 15 0 % F
% Gly: 8 0 0 0 0 8 8 0 0 0 0 0 0 58 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 15 % I
% Lys: 0 0 8 8 0 0 0 0 8 8 65 8 0 0 8 % K
% Leu: 0 8 65 0 8 0 8 0 8 72 0 50 0 8 0 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 15 0 0 8 % M
% Asn: 0 0 0 0 8 0 65 0 0 0 0 8 0 8 0 % N
% Pro: 0 65 0 0 0 15 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 8 0 8 8 0 0 0 50 0 0 % Q
% Arg: 8 8 0 0 0 0 0 0 65 0 22 0 29 0 8 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 86 0 0 15 0 8 0 65 0 0 15 15 0 0 0 % T
% Val: 0 8 8 0 72 65 8 0 8 8 0 0 8 8 8 % V
% Trp: 0 0 0 65 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _