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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A17
All Species:
22.73
Human Site:
Y252
Identified Species:
38.46
UniProt:
O43808
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43808
NP_006349.1
307
34567
Y252
G
S
L
R
N
I
L
Y
L
L
H
Q
R
V
R
Chimpanzee
Pan troglodytes
XP_515260
425
48646
Y370
G
S
L
R
N
I
L
Y
L
L
H
Q
R
V
R
Rhesus Macaque
Macaca mulatta
XP_001102293
307
34540
Y252
G
S
L
R
N
I
L
Y
L
L
H
Q
R
V
R
Dog
Lupus familis
XP_531726
307
34516
Y252
G
S
L
R
N
V
L
Y
L
L
H
Q
R
V
K
Cat
Felis silvestris
Mouse
Mus musculus
O70579
307
34394
S252
G
S
L
R
N
V
L
S
L
L
H
Q
R
V
K
Rat
Rattus norvegicus
P56499
308
33996
H254
G
R
Y
R
S
P
L
H
C
M
L
R
M
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508103
244
28142
H192
R
N
I
L
Y
L
L
H
Q
R
V
R
R
F
G
Chicken
Gallus gallus
XP_416242
335
37224
Y280
G
S
L
K
N
V
L
Y
L
L
R
E
R
V
R
Frog
Xenopus laevis
NP_001088333
310
34543
I258
L
G
S
L
R
R
V
I
Y
L
L
Q
Q
R
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728982
314
34398
T259
S
A
G
S
T
P
R
T
E
S
T
L
E
L
M
Honey Bee
Apis mellifera
XP_623636
308
34915
E254
P
P
N
A
G
I
L
E
I
L
F
Y
I
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783345
276
31233
L224
I
R
N
I
G
A
V
L
T
H
I
I
A
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39953
335
36942
R283
D
L
P
N
T
V
Q
R
H
L
L
P
L
I
K
Red Bread Mold
Neurospora crassa
Q7S2H8
333
36079
K276
V
Y
D
G
G
M
V
K
T
V
A
T
I
V
R
Conservation
Percent
Protein Identity:
100
69.4
98
96.7
N.A.
95.4
25.6
N.A.
64.1
82.3
76.1
N.A.
N.A.
47.7
49.3
N.A.
47.2
Protein Similarity:
100
71
99.3
99
N.A.
98
42.8
N.A.
69.7
87.4
88.3
N.A.
N.A.
66.5
66.8
N.A.
59.2
P-Site Identity:
100
100
100
86.6
N.A.
80
26.6
N.A.
13.3
73.3
13.3
N.A.
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
53.3
N.A.
46.6
93.3
26.6
N.A.
N.A.
13.3
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.2
22.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.5
37.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
0
0
0
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
0
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
50
8
8
8
22
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
15
8
8
36
0
0
0
0
% H
% Ile:
8
0
8
8
0
29
0
8
8
0
8
8
15
8
0
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
29
% K
% Leu:
8
8
43
15
0
8
65
8
43
65
22
8
8
15
0
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
8
% M
% Asn:
0
8
15
8
43
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
8
0
0
15
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
43
8
0
8
% Q
% Arg:
8
15
0
43
8
8
8
8
0
8
8
15
50
8
36
% R
% Ser:
8
43
8
8
8
0
0
8
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
15
0
0
8
15
0
8
8
0
8
0
% T
% Val:
8
0
0
0
0
29
22
0
0
8
8
0
0
58
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
8
0
0
36
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _